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Dual Role of CXCL8 in Maintaining the Mesenchymal State of Glioblastoma Stem Cells and M2-Like Tumor-Associated Macrophages.
Yuan W, Zhang Q, Gu D, Lu C, Dixit D, Gimple RC, Gao Y, Gao J, Li D, Shan D, Hu L, Li L, Li Y, Ci S, You H, Yan L, Chen K, Zhao N, Xu C, Lan J, Liu D, Zhang J, Shi Z, Wu Q, Yang K, Zhao L, Qiu Z, Lv D, Gao W, Yang H, Lin F, Wang Q, Man J, Li C, Tao W, Agnihotri S, Qian X, Mack SC, Zhang N, You Y, Rich JN, Sun G, Wang X. Yuan W, et al. Among authors: wu q. Clin Cancer Res. 2023 Sep 15;29(18):3779-3792. doi: 10.1158/1078-0432.CCR-22-3273. Clin Cancer Res. 2023. PMID: 37439870
Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells.
Wang X, Yang K, Wu Q, Kim LJY, Morton AR, Gimple RC, Prager BC, Shi Y, Zhou W, Bhargava S, Zhu Z, Jiang L, Tao W, Qiu Z, Zhao L, Zhang G, Li X, Agnihotri S, Mischel PS, Mack SC, Bao S, Rich JN. Wang X, et al. Among authors: wu q. Sci Transl Med. 2019 Aug 7;11(504):eaau4972. doi: 10.1126/scitranslmed.aau4972. Sci Transl Med. 2019. PMID: 31391321 Free PMC article.
Glioblastoma stem cells reprogram chromatin in vivo to generate selective therapeutic dependencies on DPY30 and phosphodiesterases.
Dixit D, Prager BC, Gimple RC, Miller TE, Wu Q, Yomtoubian S, Kidwell RL, Lv D, Zhao L, Qiu Z, Zhang G, Lee D, Park DE, Wechsler-Reya RJ, Wang X, Bao S, Rich JN. Dixit D, et al. Among authors: wu q. Sci Transl Med. 2022 Jan 5;14(626):eabf3917. doi: 10.1126/scitranslmed.abf3917. Epub 2022 Jan 5. Sci Transl Med. 2022. PMID: 34985972
Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe.
Zhang G, Dong Z, Gimple RC, Wolin A, Wu Q, Qiu Z, Wood LM, Shen JZ, Jiang L, Zhao L, Lv D, Prager BC, Kim LJY, Wang X, Zhang L, Anderson RL, Moore JK, Bao S, Keller TH, Lin G, Kang C, Hamerlik P, Zhao R, Ford HL, Rich JN. Zhang G, et al. Among authors: wu q. J Exp Med. 2021 Nov 1;218(11):e20202669. doi: 10.1084/jem.20202669. Epub 2021 Oct 7. J Exp Med. 2021. PMID: 34617969 Free PMC article.
Phage display discovery of novel molecular targets in glioblastoma-initiating cells.
Liu JK, Lubelski D, Schonberg DL, Wu Q, Hale JS, Flavahan WA, Mulkearns-Hubert EE, Man J, Hjelmeland AB, Yu J, Lathia JD, Rich JN. Liu JK, et al. Among authors: wu q. Cell Death Differ. 2014 Aug;21(8):1325-39. doi: 10.1038/cdd.2014.65. Epub 2014 May 16. Cell Death Differ. 2014. PMID: 24832468 Free PMC article.
Acidic stress promotes a glioma stem cell phenotype.
Hjelmeland AB, Wu Q, Heddleston JM, Choudhary GS, MacSwords J, Lathia JD, McLendon R, Lindner D, Sloan A, Rich JN. Hjelmeland AB, et al. Among authors: wu q. Cell Death Differ. 2011 May;18(5):829-40. doi: 10.1038/cdd.2010.150. Epub 2010 Dec 3. Cell Death Differ. 2011. PMID: 21127501 Free PMC article.
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