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Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.
Zhang HG, Wang B, Yang Y, Liu X, Wang J, Xin N, Li S, Miao Y, Wu Q, Guo T, Yuan Y, Zuo Y, Chen X, Ren T, Dong C, Wang J, Ruan H, Sun M, Xu X, Zheng H. Zhang HG, et al. Among authors: wu q. Cell Res. 2022 Oct;32(10):897-913. doi: 10.1038/s41422-022-00689-9. Epub 2022 Jul 12. Cell Res. 2022. PMID: 35821088 Free PMC article.
A Natural Plant Ingredient, Menthone, Regulates T Cell Subtypes and Lowers Pro-inflammatory Cytokines of Rheumatoid Arthritis.
Chen X, Wu Q, Gong Z, Ren T, Du Q, Yuan Y, Zuo Y, Miao Y, He J, Qiao C, Zheng Z, Zhang T, Huang L, Xie Z, Wang J, Zhu Y, Zhu C, Xu Y, Wu D, Gong F, Cheng J, Wen C, Zheng H. Chen X, et al. Among authors: wu d, wu q. J Nat Prod. 2022 Apr 22;85(4):1109-1117. doi: 10.1021/acs.jnatprod.1c01231. Epub 2022 Mar 18. J Nat Prod. 2022. PMID: 35302365 Review.
E3 ubiquitin ligase MID1 ubiquitinates and degrades type-I interferon receptor 2.
Chen X, Zhao Q, Xu Y, Wu Q, Zhang R, Du Q, Miao Y, Zuo Y, Zhang HG, Huang F, Ren T, He J, Qiao C, Li Y, Li S, Xu Y, Wu D, Yu Z, Lv H, Wang J, Zheng H, Yuan Y. Chen X, et al. Among authors: wu d, wu q. Immunology. 2022 Nov;167(3):398-412. doi: 10.1111/imm.13544. Epub 2022 Jul 23. Immunology. 2022. PMID: 35794827 Free article.
Menthone inhibits type-I interferon signaling by promoting Tyk2 ubiquitination to relieve local inflammation of rheumatoid arthritis.
Chen X, Wu Q, Cao X, Yang Y, Gong Z, Ren T, Du Q, Yuan Y, Zuo Y, Miao Y, He J, Qiao C, Zheng Z, Zhang T, Xu Y, Wu D, Wang Q, Huang L, Xie Z, Lv H, Wang J, Gong F, Liu Z, Wen C, Zheng H. Chen X, et al. Among authors: wu d, wu q. Int Immunopharmacol. 2022 Nov;112:109228. doi: 10.1016/j.intimp.2022.109228. Epub 2022 Sep 9. Int Immunopharmacol. 2022. PMID: 36095947
Ceftazidime reduces cellular Skp2 to promote type-I interferon activity.
Qiao C, Huang F, He J, Wu Q, Zheng Z, Zhang T, Miao Y, Yuan Y, Chen X, Du Q, Xu Y, Wu D, Yu Z, Zheng H. Qiao C, et al. Among authors: wu d, wu q. Immunology. 2023 Dec;170(4):527-539. doi: 10.1111/imm.13687. Epub 2023 Aug 28. Immunology. 2023. PMID: 37641430
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