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The aberrant upregulation of exon 10-inclusive SREK1 through SRSF10 acts as an oncogenic driver in human hepatocellular carcinoma.
Chang C, Rajasekaran M, Qiao Y, Dong H, Wang Y, Xia H, Deivasigamani A, Wu M, Sekar K, Gao H, Sun M, Niu Y, Li Q, Tao L, Yan Z, Wang M, Chen S, Zhao S, Chen D, Li L, Yang F, Gao H, Chen B, Su L, Xu L, Chen Y, Seshachalam VP, Chen G, Gunaratne J, Hong W, Shi J, Chen G, Grierson DS, Chabot B, Xie T, Hui KM, Chen J. Chang C, et al. Among authors: wu m. Nat Commun. 2022 Mar 16;13(1):1363. doi: 10.1038/s41467-022-29016-x. Nat Commun. 2022. PMID: 35296659 Free PMC article.
Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.
Shi C, Wang Y, Wu M, Chen Y, Liu F, Shen Z, Wang Y, Xie S, Shen Y, Sang L, Zhang Z, Gao Z, Yang L, Qu L, Yang Z, He X, Guo Y, Pan C, Che J, Ju H, Liu J, Cai Z, Yan Q, Yu L, Wang L, Dong X, Xu P, Shao J, Liu Y, Li X, Wang W, Zhou R, Zhou T, Lin A. Shi C, et al. Among authors: wu m. Nat Commun. 2022 Nov 14;13(1):6951. doi: 10.1038/s41467-022-34346-x. Nat Commun. 2022. PMID: 36376293 Free PMC article.
Mitochondrial long non-coding RNA GAS5 tunes TCA metabolism in response to nutrient stress.
Sang L, Ju HQ, Yang Z, Ge Q, Zhang Z, Liu F, Yang L, Gong H, Shi C, Qu L, Chen H, Wu M, Chen H, Li R, Zhuang Q, Piao H, Yan Q, Yu W, Wang L, Shao J, Liu J, Wang W, Zhou T, Lin A. Sang L, et al. Among authors: wu m. Nat Metab. 2021 Jan;3(1):90-106. doi: 10.1038/s42255-020-00325-z. Epub 2021 Jan 4. Nat Metab. 2021. PMID: 33398195
Immunogenicity of third dose COVID-19 vaccine strategies in patients who are immunocompromised with suboptimal immunity following two doses (OCTAVE-DUO): an open-label, multicentre, randomised, controlled, phase 3 trial.
Goodyear CS, Patel A, Barnes E, Willicombe M, Siebert S, de Silva TI, Snowden JA, Lim SH, Bowden SJ, Billingham L, Richter A, Carroll M, Carr EJ, Beale R, Rea D, Parry H, Pirrie S, Lim Z, Satsangi J, Dunachie SJ, Cook G, Miller P, Basu N, Gilmour A, Hodgkins AM, Evans L, Hughes A, Longet S, Meacham G, Yong KL, A'Hearne MJ, Koh MBC, Burns SO, Orchard K, Paterson C, McIlroy G, Murray SM, Thomson T, Dimitriadis S, Goulston L, Miller S, Keillor V, Prendecki M, Thomas D, Kirkham A, McInnes IB, Kearns P; OCTAVE-DUO investigators. Goodyear CS, et al. Lancet Rheumatol. 2024 May 8:S2665-9913(24)00065-1. doi: 10.1016/S2665-9913(24)00065-1. Online ahead of print. Lancet Rheumatol. 2024. PMID: 38734019
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