Wu LE - Search Results

1

Host-microbiome interactions in nicotinamide mononucleotide (NMN) deamidation.

Kim LJ, Chalmers TJ, Madawala R, Smith GC, Li C, Das A, Poon EWK, Wang J, Tucker SP, Sinclair DA, Quek LE, Wu LE. Kim LJ, et al. Among authors: wu le. FEBS Lett. 2023 Sep;597(17):2196-2220. doi: 10.1002/1873-3468.14698. Epub 2023 Aug 9. FEBS Lett. 2023. PMID: 37463842

2

Geroncogenesis: metabolic changes during aging as a driver of tumorigenesis.

Wu LE, Gomes AP, Sinclair DA. Wu LE, et al. Cancer Cell. 2014 Jan 13;25(1):12-9. doi: 10.1016/j.ccr.2013.12.005. Cancer Cell. 2014. PMID: 24434207 Free PMC article.

3

SIRT2 induces the checkpoint kinase BubR1 to increase lifespan.

North BJ, Rosenberg MA, Jeganathan KB, Hafner AV, Michan S, Dai J, Baker DJ, Cen Y, Wu LE, Sauve AA, van Deursen JM, Rosenzweig A, Sinclair DA. North BJ, et al. Among authors: wu le. EMBO J. 2014 Jul 1;33(13):1438-53. doi: 10.15252/embj.201386907. Epub 2014 May 12. EMBO J. 2014. PMID: 24825348 Free PMC article.

4

SIRT2 controls the pentose phosphate switch.

Wu LE, Sinclair DA. Wu LE, et al. EMBO J. 2014 Jun 17;33(12):1287-8. doi: 10.15252/embj.201488713. Epub 2014 May 13. EMBO J. 2014. PMID: 24825350 Free PMC article.

5

Nicotinamide impairs entry into and exit from meiosis I in mouse oocytes.

Riepsamen A, Wu L, Lau L, Listijono D, Ledger W, Sinclair D, Homer H. Riepsamen A, et al. PLoS One. 2015 May 4;10(5):e0126194. doi: 10.1371/journal.pone.0126194. eCollection 2015. PLoS One. 2015. PMID: 25938585 Free PMC article.

6

Niclosamide blocks glucagon phosphorylation of Ser552 on β-catenin in primary rat hepatocytes via PKA signalling.

Chowdhury MK, Wu LE, Coleman JL, Smith NJ, Morris MJ, Shepherd PR, Smith GC. Chowdhury MK, et al. Among authors: wu le. Biochem J. 2016 May 1;473(9):1247-55. doi: 10.1042/BCJ20160121. Epub 2016 Mar 10. Biochem J. 2016. PMID: 26964897

7

Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency.

Cagnone GL, Tsai TS, Makanji Y, Matthews P, Gould J, Bonkowski MS, Elgass KD, Wong AS, Wu LE, McKenzie M, Sinclair DA, St John JC. Cagnone GL, et al. Among authors: wu le. Sci Rep. 2016 Mar 18;6:23229. doi: 10.1038/srep23229. Sci Rep. 2016. PMID: 26987907 Free PMC article.

8

Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age-related insulin resistance.

Mohamad M, Mitchell SJ, Wu LE, White MY, Cordwell SJ, Mach J, Solon-Biet SM, Boyer D, Nines D, Das A, Catherine Li SY, Warren A, Hilmer SN, Fraser R, Sinclair DA, Simpson SJ, de Cabo R, Le Couteur DG, Cogger VC. Mohamad M, et al. Among authors: le couteur dg, wu le. Aging Cell. 2016 Aug;15(4):706-15. doi: 10.1111/acel.12481. Epub 2016 Apr 20. Aging Cell. 2016. PMID: 27095270 Free PMC article.

9

Restoring stem cells - all you need is NAD(.).

Wu LE, Sinclair DA. Wu LE, et al. Cell Res. 2016 Sep;26(9):971-2. doi: 10.1038/cr.2016.80. Epub 2016 Jun 24. Cell Res. 2016. PMID: 27339086 Free PMC article.

10

Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes.

Chowdhury MK, Turner N, Bentley NL, Das A, Wu LE, Richani D, Bustamante S, Gilchrist RB, Morris MJ, Shepherd PR, Smith GC. Chowdhury MK, et al. Among authors: wu le. Sci Rep. 2017 Jan 5;7:40159. doi: 10.1038/srep40159. Sci Rep. 2017. PMID: 28054648 Free PMC article.

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