Wu H - Search Results

1

HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation.

Magupalli VG, Negro R, Tian Y, Hauenstein AV, Di Caprio G, Skillern W, Deng Q, Orning P, Alam HB, Maliga Z, Sharif H, Hu JJ, Evavold CL, Kagan JC, Schmidt FI, Fitzgerald KA, Kirchhausen T, Li Y, Wu H. Magupalli VG, et al. Among authors: wu h. Science. 2020 Sep 18;369(6510):eaas8995. doi: 10.1126/science.aas8995. Science. 2020. PMID: 32943500 Free PMC article.

2

Anticancer flavonoids are mouse-selective STING agonists.

Kim S, Li L, Maliga Z, Yin Q, Wu H, Mitchison TJ. Kim S, et al. Among authors: wu h. ACS Chem Biol. 2013 Jul 19;8(7):1396-401. doi: 10.1021/cb400264n. Epub 2013 May 23. ACS Chem Biol. 2013. PMID: 23683494 Free PMC article.

3

Molecular mechanism for p202-mediated specific inhibition of AIM2 inflammasome activation.

Yin Q, Sester DP, Tian Y, Hsiao YS, Lu A, Cridland JA, Sagulenko V, Thygesen SJ, Choubey D, Hornung V, Walz T, Stacey KJ, Wu H. Yin Q, et al. Among authors: wu h. Cell Rep. 2013 Jul 25;4(2):327-39. doi: 10.1016/j.celrep.2013.06.024. Epub 2013 Jul 11. Cell Rep. 2013. PMID: 23850291 Free PMC article.

4

Crystal structure of the F27G AIM2 PYD mutant and similarities of its self-association to DED/DED interactions.

Lu A, Kabaleeswaran V, Fu T, Magupalli VG, Wu H. Lu A, et al. Among authors: wu h. J Mol Biol. 2014 Apr 3;426(7):1420-7. doi: 10.1016/j.jmb.2013.12.029. Epub 2014 Jan 7. J Mol Biol. 2014. PMID: 24406744 Free PMC article.

5

Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.

Lu A, Magupalli VG, Ruan J, Yin Q, Atianand MK, Vos MR, Schröder GF, Fitzgerald KA, Wu H, Egelman EH. Lu A, et al. Among authors: wu h. Cell. 2014 Mar 13;156(6):1193-1206. doi: 10.1016/j.cell.2014.02.008. Cell. 2014. PMID: 24630722 Free PMC article.

6

Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs.

Li L, Yin Q, Kuss P, Maliga Z, Millán JL, Wu H, Mitchison TJ. Li L, et al. Among authors: wu h. Nat Chem Biol. 2014 Dec;10(12):1043-8. doi: 10.1038/nchembio.1661. Epub 2014 Oct 26. Nat Chem Biol. 2014. PMID: 25344812 Free PMC article.

7

Structural mechanisms of inflammasome assembly.

Lu A, Wu H. Lu A, et al. Among authors: wu h. FEBS J. 2015 Feb;282(3):435-44. doi: 10.1111/febs.13133. Epub 2014 Nov 21. FEBS J. 2015. PMID: 25354325 Free PMC article. Review.

8

SMOCs: supramolecular organizing centres that control innate immunity.

Kagan JC, Magupalli VG, Wu H. Kagan JC, et al. Among authors: wu h. Nat Rev Immunol. 2014 Dec;14(12):821-6. doi: 10.1038/nri3757. Epub 2014 Oct 31. Nat Rev Immunol. 2014. PMID: 25359439 Free PMC article. Review.

9

The hierarchical structural architecture of inflammasomes, supramolecular inflammatory machines.

Hauenstein AV, Zhang L, Wu H. Hauenstein AV, et al. Among authors: wu h. Curr Opin Struct Biol. 2015 Apr;31:75-83. doi: 10.1016/j.sbi.2015.03.014. Epub 2015 Apr 13. Curr Opin Struct Biol. 2015. PMID: 25881155 Free PMC article. Review.

10

Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.

Zhang L, Chen S, Ruan J, Wu J, Tong AB, Yin Q, Li Y, David L, Lu A, Wang WL, Marks C, Ouyang Q, Zhang X, Mao Y, Wu H. Zhang L, et al. Among authors: wu h, wu j. Science. 2015 Oct 23;350(6259):404-9. doi: 10.1126/science.aac5789. Epub 2015 Oct 8. Science. 2015. PMID: 26449474 Free PMC article.

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