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Cryo-EM structure of the DNA-PK holoenzyme.
Sharif H, Li Y, Dong Y, Dong L, Wang WL, Mao Y, Wu H. Sharif H, et al. Among authors: wu h. Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):7367-7372. doi: 10.1073/pnas.1707386114. Epub 2017 Jun 26. Proc Natl Acad Sci U S A. 2017. PMID: 28652322 Free PMC article.
Crystal structure of human IRAK1.
Wang L, Qiao Q, Ferrao R, Shen C, Hatcher JM, Buhrlage SJ, Gray NS, Wu H. Wang L, et al. Among authors: wu h. Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):13507-13512. doi: 10.1073/pnas.1714386114. Epub 2017 Dec 5. Proc Natl Acad Sci U S A. 2017. PMID: 29208712 Free PMC article.
Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome.
David L, Li Y, Ma J, Garner E, Zhang X, Wu H. David L, et al. Among authors: wu h. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1499-1504. doi: 10.1073/pnas.1721967115. Epub 2018 Jan 30. Proc Natl Acad Sci U S A. 2018. PMID: 29382759 Free PMC article.
Mechanism of ubiquitin transfer promoted by TRAF6.
Fu TM, Shen C, Li Q, Zhang P, Wu H. Fu TM, et al. Among authors: wu h. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1783-1788. doi: 10.1073/pnas.1721788115. Epub 2018 Feb 5. Proc Natl Acad Sci U S A. 2018. PMID: 29432170 Free PMC article.
Structures and gating mechanism of human TRPM2.
Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H. Wang L, et al. Among authors: wu h. Science. 2018 Dec 21;362(6421):eaav4809. doi: 10.1126/science.aav4809. Epub 2018 Nov 22. Science. 2018. PMID: 30467180 Free PMC article.
Crystal structure of the WD40 domain dimer of LRRK2.
Zhang P, Fan Y, Ru H, Wang L, Magupalli VG, Taylor SS, Alessi DR, Wu H. Zhang P, et al. Among authors: wu h. Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1579-1584. doi: 10.1073/pnas.1817889116. Epub 2019 Jan 11. Proc Natl Acad Sci U S A. 2019. PMID: 30635421 Free PMC article.
Molecular mechanism for NLRP6 inflammasome assembly and activation.
Shen C, Lu A, Xie WJ, Ruan J, Negro R, Egelman EH, Fu TM, Wu H. Shen C, et al. Among authors: wu h. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2052-2057. doi: 10.1073/pnas.1817221116. Epub 2019 Jan 23. Proc Natl Acad Sci U S A. 2019. PMID: 30674671 Free PMC article.
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