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PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension.
Cao Y, Zhang X, Wang L, Yang Q, Ma Q, Xu J, Wang J, Kovacs L, Ayon RJ, Liu Z, Zhang M, Zhou Y, Zeng X, Xu Y, Wang Y, Fulton DJ, Weintraub NL, Lucas R, Dong Z, Yuan JX, Sullivan JC, Meadows L, Barman SA, Wu C, Quan J, Hong M, Su Y, Huo Y. Cao Y, et al. Among authors: wu c. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13394-13403. doi: 10.1073/pnas.1821401116. Epub 2019 Jun 18. Proc Natl Acad Sci U S A. 2019. PMID: 31213542 Free PMC article.
Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses.
Huo Y, Guo X, Li H, Xu H, Halim V, Zhang W, Wang H, Fan YY, Ong KT, Woo SL, Chapkin RS, Mashek DG, Chen Y, Dong H, Lu F, Wei L, Wu C. Huo Y, et al. Among authors: wu c. J Biol Chem. 2012 Jun 15;287(25):21492-500. doi: 10.1074/jbc.M112.370379. Epub 2012 May 3. J Biol Chem. 2012. PMID: 22556414 Free PMC article.
Endothelial PFKFB3 plays a critical role in angiogenesis.
Xu Y, An X, Guo X, Habtetsion TG, Wang Y, Xu X, Kandala S, Li Q, Li H, Zhang C, Caldwell RB, Fulton DJ, Su Y, Hoda MN, Zhou G, Wu C, Huo Y. Xu Y, et al. Among authors: wu c. Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1231-9. doi: 10.1161/ATVBAHA.113.303041. Epub 2014 Apr 3. Arterioscler Thromb Vasc Biol. 2014. PMID: 24700124 Free PMC article.
Metformin and metabolic diseases: a focus on hepatic aspects.
Zheng J, Woo SL, Hu X, Botchlett R, Chen L, Huo Y, Wu C. Zheng J, et al. Among authors: wu c. Front Med. 2015 Jun;9(2):173-86. doi: 10.1007/s11684-015-0384-0. Epub 2015 Feb 12. Front Med. 2015. PMID: 25676019 Free PMC article. Review.
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