Wu B - Search Results

1

Double-Winged 3-Hydroxypyrimidine-2,4-diones: Potent and Selective Inhibition against HIV-1 RNase H with Significant Antiviral Activity.

Vernekar SKV, Tang J, Wu B, Huber AD, Casey MC, Myshakina N, Wilson DJ, Kankanala J, Kirby KA, Parniak MA, Sarafianos SG, Wang Z. Vernekar SKV, et al. Among authors: wu b. J Med Chem. 2017 Jun 22;60(12):5045-5056. doi: 10.1021/acs.jmedchem.7b00440. Epub 2017 May 31. J Med Chem. 2017. PMID: 28525279 Free PMC article.

2

3-Hydroxypyrimidine-2,4-diones as Selective Active Site Inhibitors of HIV Reverse Transcriptase-Associated RNase H: Design, Synthesis, and Biochemical Evaluations.

Tang J, Liu F, Nagy E, Miller L, Kirby KA, Wilson DJ, Wu B, Sarafianos SG, Parniak MA, Wang Z. Tang J, et al. Among authors: wu b. J Med Chem. 2016 Mar 24;59(6):2648-59. doi: 10.1021/acs.jmedchem.5b01879. Epub 2016 Mar 8. J Med Chem. 2016. PMID: 26927866 Free PMC article.

3

3-Hydroxypyrimidine-2,4-dione-5-N-benzylcarboxamides Potently Inhibit HIV-1 Integrase and RNase H.

Wu B, Tang J, Wilson DJ, Huber AD, Casey MC, Ji J, Kankanala J, Xie J, Sarafianos SG, Wang Z. Wu B, et al. J Med Chem. 2016 Jul 14;59(13):6136-48. doi: 10.1021/acs.jmedchem.6b00040. Epub 2016 Jun 17. J Med Chem. 2016. PMID: 27283261 Free PMC article.

4

Synthesis and Structure-Activity Relationship Study of 5a-Carbasugar Analogues of SL0101.

Li M, Li Y, Mrozowski RM, Sandusky ZM, Shan M, Song X, Wu B, Zhang Q, Lannigan DA, O'Doherty GA. Li M, et al. Among authors: wu b. ACS Med Chem Lett. 2014 Nov 26;6(1):95-9. doi: 10.1021/ml5004525. eCollection 2015 Jan 8. ACS Med Chem Lett. 2014. PMID: 25589938 Free PMC article.

5

C5'-Alkyl Substitution Effects on Digitoxigenin α-l-Glycoside Cancer Cytotoxicity.

Wang HY, Qi Z, Wu B, Kang SW, Rojanasakul Y, O'Doherty GA. Wang HY, et al. Among authors: wu b. ACS Med Chem Lett. 2011 Apr 14;2(4):259-263. doi: 10.1021/ml100291n. ACS Med Chem Lett. 2011. PMID: 21572583 Free PMC article.

6

Improving the affinity of SL0101 for RSK using structure-based design.

Mrozowski RM, Vemula R, Wu B, Zhang Q, Schroeder BR, Hilinski MK, Clark DE, Hecht SM, O'Doherty GA, Lannigan DA. Mrozowski RM, et al. Among authors: wu b. ACS Med Chem Lett. 2012 Feb 14;4(2):175-179. doi: 10.1021/ml300298v. Epub 2012 Dec 26. ACS Med Chem Lett. 2012. PMID: 23519677 Free PMC article.

7

De novo synthesis and biological evaluation of C6″-substituted C4″-amide analogues of SL0101.

Mrozowski RM, Sandusky ZM, Vemula R, Wu B, Zhang Q, Lannigan DA, O'Doherty GA. Mrozowski RM, et al. Among authors: wu b. Org Lett. 2014 Nov 21;16(22):5996-9. doi: 10.1021/ol503012k. Epub 2014 Nov 5. Org Lett. 2014. PMID: 25372628 Free PMC article.

8

Structure Activity Relationship Study of the Cleistriosides and Cleistetrosides for Antibacterial/Anticancer Activity.

Shi P, Silva MC, Wang HY, Wu B, Akhmedov NG, Li M, Beuning PJ, O'Doherty GA. Shi P, et al. Among authors: wu b. ACS Med Chem Lett. 2012 Dec 13;3(12):1086-1090. doi: 10.1021/ml300303g. Epub 2012 Oct 30. ACS Med Chem Lett. 2012. PMID: 23543830 Free PMC article.

9

Regioselective Synthesis of a C-4'' Carbamate,C-6'' n-Pr Substituted Cyclitol Analogue of SL0101.

Li Y, Sandusky ZM, Vemula R, Zhang Q, Wu B, Fukuda S, Li M, Lannigan DA, O'Doherty GA. Li Y, et al. Among authors: wu b. Org Lett. 2020 Feb 21;22(4):1448-1452. doi: 10.1021/acs.orglett.0c00042. Epub 2020 Feb 3. Org Lett. 2020. PMID: 32009414 Free PMC article.

10

A de novo approach to the synthesis of glycosylated methymycin analogues with structural and stereochemical diversity.

Borisova SA, Guppi SR, Kim HJ, Wu B, Penn JH, Liu HW, O'Doherty GA. Borisova SA, et al. Among authors: wu b. Org Lett. 2010 Nov 19;12(22):5150-3. doi: 10.1021/ol102144g. Epub 2010 Oct 19. Org Lett. 2010. PMID: 20958086 Free PMC article.

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