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The conduct of in vitro and in vivo drug-drug interaction studies: a PhRMA perspective.
Bjornsson TD, Callaghan JT, Einolf HJ, Fischer V, Gan L, Grimm S, Kao J, King SP, Miwa G, Ni L, Kumar G, McLeod J, Obach SR, Roberts S, Roe A, Shah A, Snikeris F, Sullivan JT, Tweedie D, Vega JM, Walsh J, Wrighton SA; Pharmaceutical Research and Manufacturers of America Drug Metabolism/Clinical Pharmacology Technical Working Groups. Bjornsson TD, et al. Among authors: wrighton sa. J Clin Pharmacol. 2003 May;43(5):443-69. J Clin Pharmacol. 2003. PMID: 12751267 Review.
The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspective.
Bjornsson TD, Callaghan JT, Einolf HJ, Fischer V, Gan L, Grimm S, Kao J, King SP, Miwa G, Ni L, Kumar G, McLeod J, Obach RS, Roberts S, Roe A, Shah A, Snikeris F, Sullivan JT, Tweedie D, Vega JM, Walsh J, Wrighton SA; Pharmaceutical Research and Manufacturers of America (PhRMA) Drug Metabolism/Clinical Pharmacology Technical Working Group; FDA Center for Drug Evaluation and Research (CDER). Bjornsson TD, et al. Among authors: wrighton sa. Drug Metab Dispos. 2003 Jul;31(7):815-32. doi: 10.1124/dmd.31.7.815. Drug Metab Dispos. 2003. PMID: 12814957
PhRMA white paper on ADME pharmacogenomics.
Williams JA, Andersson T, Andersson TB, Blanchard R, Behm MO, Cohen N, Edeki T, Franc M, Hillgren KM, Johnson KJ, Katz DA, Milton MN, Murray BP, Polli JW, Ricci D, Shipley LA, Vangala S, Wrighton SA. Williams JA, et al. Among authors: wrighton sa. J Clin Pharmacol. 2008 Jul;48(7):849-89. doi: 10.1177/0091270008319329. Epub 2008 Jun 4. J Clin Pharmacol. 2008. PMID: 18524998 Review.
Autoactivation and activation of the cytochrome P450s.
Ekins S, Ring BJ, Binkley SN, Hall SD, Wrighton SA. Ekins S, et al. Among authors: wrighton sa. Int J Clin Pharmacol Ther. 1998 Dec;36(12):642-51. Int J Clin Pharmacol Ther. 1998. PMID: 9877001
Present and future in vitro approaches for drug metabolism.
Ekins S, Ring BJ, Grace J, McRobie-Belle DJ, Wrighton SA. Ekins S, et al. Among authors: wrighton sa. J Pharmacol Toxicol Methods. 2000 Jul-Aug;44(1):313-24. doi: 10.1016/s1056-8719(00)00110-6. J Pharmacol Toxicol Methods. 2000. PMID: 11274898 Review.
180 results