Wright SD - Search Results

1

Inhibition of VEGF-B signaling prevents non-alcoholic fatty liver disease development by targeting lipolysis in the white adipose tissue.

Falkevall A, Mehlem A, Folestad E, Ning FC, Osorio-Conles Ó, Radmann R, de Hollanda A, Wright SD, Scotney P, Nash A, Eriksson U. Falkevall A, et al. Among authors: wright sd. J Hepatol. 2023 May;78(5):901-913. doi: 10.1016/j.jhep.2023.01.014. Epub 2023 Jan 27. J Hepatol. 2023. PMID: 36717026 Free article.

2

Moderate Renal Impairment Does Not Impact the Ability of CSL112 (Apolipoprotein A-I [Human]) to Enhance Cholesterol Efflux Capacity.

Gille A, Duffy D, Tortorici MA, Wright SD, Deckelbaum LI, D'Andrea DM. Gille A, et al. Among authors: wright sd. J Clin Pharmacol. 2019 Mar;59(3):427-436. doi: 10.1002/jcph.1337. Epub 2018 Nov 19. J Clin Pharmacol. 2019. PMID: 30452776 Free PMC article. Clinical Trial.

3

A multiple ascending dose study of CSL112, an infused formulation of ApoA-I.

Easton R, Gille A, D'Andrea D, Davis R, Wright SD, Shear C. Easton R, et al. Among authors: wright sd. J Clin Pharmacol. 2014 Mar;54(3):301-10. doi: 10.1002/jcph.194. Epub 2013 Oct 22. J Clin Pharmacol. 2014. PMID: 24122814 Clinical Trial.

4

Pharmacometric analyses to characterize the effect of CSL112 on apolipoprotein A-I and cholesterol efflux capacity in acute myocardial infarction patients.

Zheng B, Duffy D, Tricoci P, Kastrissios H, Pfister M, Wright SD, Gille A, Tortorici MA. Zheng B, et al. Among authors: wright sd. Br J Clin Pharmacol. 2021 Jun;87(6):2558-2571. doi: 10.1111/bcp.14666. Epub 2020 Dec 23. Br J Clin Pharmacol. 2021. PMID: 33217027 Free PMC article. Clinical Trial.

5

CSL112 enhances biomarkers of reverse cholesterol transport after single and multiple infusions in healthy subjects.

Gille A, Easton R, D'Andrea D, Wright SD, Shear CL. Gille A, et al. Among authors: wright sd. Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):2106-14. doi: 10.1161/ATVBAHA.114.303720. Epub 2014 Jun 26. Arterioscler Thromb Vasc Biol. 2014. PMID: 24969776 Clinical Trial.

6

CSL112 (Apolipoprotein A-I [Human]) Enhances Cholesterol Efflux Similarly in Healthy Individuals and Stable Atherosclerotic Disease Patients.

Gille A, D'Andrea D, Tortorici MA, Hartel G, Wright SD. Gille A, et al. Among authors: wright sd. Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):953-963. doi: 10.1161/ATVBAHA.118.310538. Epub 2018 Feb 8. Arterioscler Thromb Vasc Biol. 2018. PMID: 29437574 Free PMC article. Clinical Trial.

7

Nascent HDL (High-Density Lipoprotein) Discs Carry Cholesterol to HDL Spheres: Effects of HDL Particle Remodeling on Cholesterol Efflux.

Navdaev AV, Sborgi L, Wright SD, Didichenko SA. Navdaev AV, et al. Among authors: wright sd. Arterioscler Thromb Vasc Biol. 2020 May;40(5):1182-1194. doi: 10.1161/ATVBAHA.120.313906. Epub 2020 Mar 5. Arterioscler Thromb Vasc Biol. 2020. PMID: 32131613 Free PMC article.

8

CSL112 Infusion Rapidly Increases APOA1 Exchange Rate via Specific Serum Amyloid-Poor HDL Subpopulations When Administered to Patients Post-Myocardial Infarction.

Didichenko SA, Velkoska E, Navdaev AV, Greene BH, Lorkowski SW, Duffy D, Mears SJ, Wright SD, Gibson CM, Smith JD, Kingwell BA. Didichenko SA, et al. Among authors: wright sd. Arterioscler Thromb Vasc Biol. 2023 Jun;43(6):855-869. doi: 10.1161/ATVBAHA.122.318243. Epub 2023 Mar 30. Arterioscler Thromb Vasc Biol. 2023. PMID: 36994730 Free article.

9

Pharmacokinetics and Safety of CSL112 (Apolipoprotein A-I [Human]) in Adults With Moderate Renal Impairment and Normal Renal Function.

Tortorici MA, Duffy D, Evans R, Feaster J, Gille A, Mant TGK, Wright SD, D'Andrea D. Tortorici MA, et al. Among authors: wright sd. Clin Pharmacol Drug Dev. 2019 Jul;8(5):628-636. doi: 10.1002/cpdd.618. Epub 2018 Sep 21. Clin Pharmacol Drug Dev. 2019. PMID: 30240132 Free PMC article. Clinical Trial.

10

Novel formulation of a reconstituted high-density lipoprotein (CSL112) dramatically enhances ABCA1-dependent cholesterol efflux.

Diditchenko S, Gille A, Pragst I, Stadler D, Waelchli M, Hamilton R, Leis A, Wright SD. Diditchenko S, et al. Among authors: wright sd. Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2202-11. doi: 10.1161/ATVBAHA.113.301981. Epub 2013 Jul 18. Arterioscler Thromb Vasc Biol. 2013. PMID: 23868939

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