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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nuñez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E. Duewell P, et al. Among authors: wright sd. Nature. 2010 Apr 29;464(7293):1357-61. doi: 10.1038/nature08938. Nature. 2010. PMID: 20428172 Free PMC article.
High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.
De Nardo D, Labzin LI, Kono H, Seki R, Schmidt SV, Beyer M, Xu D, Zimmer S, Lahrmann C, Schildberg FA, Vogelhuber J, Kraut M, Ulas T, Kerksiek A, Krebs W, Bode N, Grebe A, Fitzgerald ML, Hernandez NJ, Williams BR, Knolle P, Kneilling M, Röcken M, Lütjohann D, Wright SD, Schultze JL, Latz E. De Nardo D, et al. Among authors: wright sd. Nat Immunol. 2014 Feb;15(2):152-60. doi: 10.1038/ni.2784. Epub 2013 Dec 8. Nat Immunol. 2014. PMID: 24317040 Free PMC article.
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Björkhem I, Gustafsson JÅ, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, Lütjohann D, Latz E. Zimmer S, et al. Among authors: wright sd. Sci Transl Med. 2016 Apr 6;8(333):333ra50. doi: 10.1126/scitranslmed.aad6100. Sci Transl Med. 2016. PMID: 27053774 Free PMC article.
A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease.
PrabhuDas MR, Baldwin CL, Bollyky PL, Bowdish DME, Drickamer K, Febbraio M, Herz J, Kobzik L, Krieger M, Loike J, McVicker B, Means TK, Moestrup SK, Post SR, Sawamura T, Silverstein S, Speth RC, Telfer JC, Thiele GM, Wang XY, Wright SD, El Khoury J. PrabhuDas MR, et al. Among authors: wright sd. J Immunol. 2017 May 15;198(10):3775-3789. doi: 10.4049/jimmunol.1700373. J Immunol. 2017. PMID: 28483986 Free PMC article.
CSL112 Infusion Rapidly Increases APOA1 Exchange Rate via Specific Serum Amyloid-Poor HDL Subpopulations When Administered to Patients Post-Myocardial Infarction.
Didichenko SA, Velkoska E, Navdaev AV, Greene BH, Lorkowski SW, Duffy D, Mears SJ, Wright SD, Gibson CM, Smith JD, Kingwell BA. Didichenko SA, et al. Among authors: wright sd. Arterioscler Thromb Vasc Biol. 2023 Jun;43(6):855-869. doi: 10.1161/ATVBAHA.122.318243. Epub 2023 Mar 30. Arterioscler Thromb Vasc Biol. 2023. PMID: 36994730 Free article.
Biological basis and proposed mechanism of action of CSL112 (apolipoprotein A-I [human]) for prevention of major adverse cardiovascular events in patients with myocardial infarction.
Korjian S, Kazmi SHA, Chi G, Kalayci A, Lee JJ, Talib U, Wright SD, Duffy D, Kingwell BA, Mehran R, Ridker PM, Gibson CM. Korjian S, et al. Among authors: wright sd. Eur Heart J Cardiovasc Pharmacother. 2023 Jun 2;9(4):387-398. doi: 10.1093/ehjcvp/pvad014. Eur Heart J Cardiovasc Pharmacother. 2023. PMID: 36787889 Free PMC article. Review.
CSL112 (Apolipoprotein A-I [Human]) Strongly Enhances Plasma Apoa-I and Cholesterol Efflux Capacity in Post-Acute Myocardial Infarction Patients: A PK/PD Substudy of the AEGIS-I Trial.
Gibson CM, Kazmi SHA, Korjian S, Chi G, Phillips AT, Montazerin SM, Duffy D, Zheng B, Heise M, Liss C, Deckelbaum LI, Wright SD, Gille A. Gibson CM, et al. Among authors: wright sd. J Cardiovasc Pharmacol Ther. 2022 Jan-Dec;27:10742484221121507. doi: 10.1177/10742484221121507. J Cardiovasc Pharmacol Ther. 2022. PMID: 36282079 Free article. Clinical Trial.
ApoA-I Infusion Therapies Following Acute Coronary Syndrome: Past, Present, and Future.
Kalayci A, Gibson CM, Ridker PM, Wright SD, Kingwell BA, Korjian S, Chi G, Lee JJ, Tricoci P, Kazmi SH, Fitzgerald C, Shaunik A, Berman G, Duffy D, Libby P. Kalayci A, et al. Among authors: wright sd. Curr Atheroscler Rep. 2022 Jul;24(7):585-597. doi: 10.1007/s11883-022-01025-7. Epub 2022 May 7. Curr Atheroscler Rep. 2022. PMID: 35524914 Free PMC article. Review.
261 results