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The future of fungi: threats and opportunities.
Case NT, Berman J, Blehert DS, Cramer RA, Cuomo C, Currie CR, Ene IV, Fisher MC, Fritz-Laylin LK, Gerstein AC, Glass NL, Gow NAR, Gurr SJ, Hittinger CT, Hohl TM, Iliev ID, James TY, Jin H, Klein BS, Kronstad JW, Lorch JM, McGovern V, Mitchell AP, Segre JA, Shapiro RS, Sheppard DC, Sil A, Stajich JE, Stukenbrock EE, Taylor JW, Thompson D, Wright GD, Heitman J, Cowen LE. Case NT, et al. Among authors: wright gd. G3 (Bethesda). 2022 Nov 4;12(11):jkac224. doi: 10.1093/g3journal/jkac224. G3 (Bethesda). 2022. PMID: 36179219 Free PMC article.
Role of homoserine transacetylase as a new target for antifungal agents.
Nazi I, Scott A, Sham A, Rossi L, Williamson PR, Kronstad JW, Wright GD. Nazi I, et al. Among authors: wright gd. Antimicrob Agents Chemother. 2007 May;51(5):1731-6. doi: 10.1128/AAC.01400-06. Epub 2007 Mar 12. Antimicrob Agents Chemother. 2007. PMID: 17353245 Free PMC article.
Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture.
Fisher MC, Gurr SJ, Cuomo CA, Blehert DS, Jin H, Stukenbrock EH, Stajich JE, Kahmann R, Boone C, Denning DW, Gow NAR, Klein BS, Kronstad JW, Sheppard DC, Taylor JW, Wright GD, Heitman J, Casadevall A, Cowen LE. Fisher MC, et al. Among authors: wright gd. mBio. 2020 May 5;11(3):e00449-20. doi: 10.1128/mBio.00449-20. mBio. 2020. PMID: 32371596 Free PMC article. Review.
Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation.
Revie NM, Iyer KR, Maxson ME, Zhang J, Yan S, Fernandes CM, Meyer KJ, Chen X, Skulska I, Fogal M, Sanchez H, Hossain S, Li S, Yashiroda Y, Hirano H, Yoshida M, Osada H, Boone C, Shapiro RS, Andes DR, Wright GD, Nodwell JR, Del Poeta M, Burke MD, Whitesell L, Robbins N, Cowen LE. Revie NM, et al. Among authors: wright gd. Nat Commun. 2022 Jun 25;13(1):3634. doi: 10.1038/s41467-022-31308-1. Nat Commun. 2022. PMID: 35752611 Free PMC article.
Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity.
Puumala E, Sychantha D, Lach E, Reeves S, Nabeela S, Fogal M, Nigam A, Johnson JW, Aspuru-Guzik A, Shapiro RS, Uppuluri P, Kalyaanamoorthy S, Magolan J, Whitesell L, Robbins N, Wright GD, Cowen LE. Puumala E, et al. Among authors: wright gd. Cell Chem Biol. 2024 Apr 18;31(4):760-775.e17. doi: 10.1016/j.chembiol.2024.01.010. Epub 2024 Feb 22. Cell Chem Biol. 2024. PMID: 38402621 Free article.
The past, present, and future of antibiotics.
Cook MA, Wright GD. Cook MA, et al. Among authors: wright gd. Sci Transl Med. 2022 Aug 10;14(657):eabo7793. doi: 10.1126/scitranslmed.abo7793. Epub 2022 Aug 10. Sci Transl Med. 2022. PMID: 35947678 Review.
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