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Rox, a Rifamycin Resistance Enzyme with an Unprecedented Mechanism of Action.
Koteva K, Cox G, Kelso JK, Surette MD, Zubyk HL, Ejim L, Stogios P, Savchenko A, Sørensen D, Wright GD. Koteva K, et al. Among authors: wright gd. Cell Chem Biol. 2018 Apr 19;25(4):403-412.e5. doi: 10.1016/j.chembiol.2018.01.009. Epub 2018 Feb 1. Cell Chem Biol. 2018. PMID: 29398560 Free article.
Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture.
Fisher MC, Gurr SJ, Cuomo CA, Blehert DS, Jin H, Stukenbrock EH, Stajich JE, Kahmann R, Boone C, Denning DW, Gow NAR, Klein BS, Kronstad JW, Sheppard DC, Taylor JW, Wright GD, Heitman J, Casadevall A, Cowen LE. Fisher MC, et al. Among authors: wright gd. mBio. 2020 May 5;11(3):e00449-20. doi: 10.1128/mBio.00449-20. mBio. 2020. PMID: 32371596 Free PMC article. Review.
Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation.
Revie NM, Iyer KR, Maxson ME, Zhang J, Yan S, Fernandes CM, Meyer KJ, Chen X, Skulska I, Fogal M, Sanchez H, Hossain S, Li S, Yashiroda Y, Hirano H, Yoshida M, Osada H, Boone C, Shapiro RS, Andes DR, Wright GD, Nodwell JR, Del Poeta M, Burke MD, Whitesell L, Robbins N, Cowen LE. Revie NM, et al. Among authors: wright gd. Nat Commun. 2022 Jun 25;13(1):3634. doi: 10.1038/s41467-022-31308-1. Nat Commun. 2022. PMID: 35752611 Free PMC article.
The future of fungi: threats and opportunities.
Case NT, Berman J, Blehert DS, Cramer RA, Cuomo C, Currie CR, Ene IV, Fisher MC, Fritz-Laylin LK, Gerstein AC, Glass NL, Gow NAR, Gurr SJ, Hittinger CT, Hohl TM, Iliev ID, James TY, Jin H, Klein BS, Kronstad JW, Lorch JM, McGovern V, Mitchell AP, Segre JA, Shapiro RS, Sheppard DC, Sil A, Stajich JE, Stukenbrock EE, Taylor JW, Thompson D, Wright GD, Heitman J, Cowen LE. Case NT, et al. Among authors: wright gd. G3 (Bethesda). 2022 Nov 4;12(11):jkac224. doi: 10.1093/g3journal/jkac224. G3 (Bethesda). 2022. PMID: 36179219 Free PMC article.
Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity.
Puumala E, Sychantha D, Lach E, Reeves S, Nabeela S, Fogal M, Nigam A, Johnson JW, Aspuru-Guzik A, Shapiro RS, Uppuluri P, Kalyaanamoorthy S, Magolan J, Whitesell L, Robbins N, Wright GD, Cowen LE. Puumala E, et al. Among authors: wright gd. Cell Chem Biol. 2024 Apr 18;31(4):760-775.e17. doi: 10.1016/j.chembiol.2024.01.010. Epub 2024 Feb 22. Cell Chem Biol. 2024. PMID: 38402621 Free article.
394 results