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Exploring the scope of new arylamino alcohol derivatives: Synthesis, antimalarial evaluation, toxicological studies, and target exploration.
Quiliano M, Mendoza A, Fong KY, Pabón A, Goldfarb NE, Fabing I, Vettorazzi A, López de Cerain A, Dunn BM, Garavito G, Wright DW, Deharo E, Pérez-Silanes S, Aldana I, Galiano S. Quiliano M, et al. Among authors: wright dw. Int J Parasitol Drugs Drug Resist. 2016 Dec;6(3):184-198. doi: 10.1016/j.ijpddr.2016.09.004. Epub 2016 Sep 28. Int J Parasitol Drugs Drug Resist. 2016. PMID: 27718413 Free PMC article.
Identification of β-hematin inhibitors in the MMV Malaria Box.
Fong KY, Sandlin RD, Wright DW. Fong KY, et al. Among authors: wright dw. Int J Parasitol Drugs Drug Resist. 2015 Jun 6;5(3):84-91. doi: 10.1016/j.ijpddr.2015.05.003. eCollection 2015 Dec. Int J Parasitol Drugs Drug Resist. 2015. PMID: 26150923 Free PMC article.
Structure-activity relationship of new antimalarial 1-aryl-3-susbtituted propanol derivatives: Synthesis, preliminary toxicity profiling, parasite life cycle stage studies, target exploration, and targeted delivery.
Quiliano M, Pabón A, Moles E, Bonilla-Ramirez L, Fabing I, Fong KY, Nieto-Aco DA, Wright DW, Pizarro JC, Vettorazzi A, López de Cerain A, Deharo E, Fernández-Busquets X, Garavito G, Aldana I, Galiano S. Quiliano M, et al. Among authors: wright dw. Eur J Med Chem. 2018 May 25;152:489-514. doi: 10.1016/j.ejmech.2018.04.038. Epub 2018 Apr 24. Eur J Med Chem. 2018. PMID: 29754074
Hemozoin and antimalarial drug discovery.
Fong KY, Wright DW. Fong KY, et al. Among authors: wright dw. Future Med Chem. 2013 Aug;5(12):1437-50. doi: 10.4155/fmc.13.113. Future Med Chem. 2013. PMID: 23919553 Free PMC article. Review.
Lipophilic mediated assays for beta-hematin inhibitors.
Carter MD, Phelan VV, Sandlin RD, Bachmann BO, Wright DW. Carter MD, et al. Among authors: wright dw. Comb Chem High Throughput Screen. 2010 Mar;13(3):285-92. doi: 10.2174/138620710790980496. Comb Chem High Throughput Screen. 2010. PMID: 20230372 Free PMC article.
462 results