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Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.
Schenk T, Chen WC, Göllner S, Howell L, Jin L, Hebestreit K, Klein HU, Popescu AC, Burnett A, Mills K, Casero RA Jr, Marton L, Woster P, Minden MD, Dugas M, Wang JC, Dick JE, Müller-Tidow C, Petrie K, Zelent A. Schenk T, et al. Nat Med. 2012 Mar 11;18(4):605-11. doi: 10.1038/nm.2661. Nat Med. 2012. PMID: 22406747 Free PMC article.
Polyamine catabolism and oxidative damage.
Murray Stewart T, Dunston TT, Woster PM, Casero RA Jr. Murray Stewart T, et al. Among authors: woster pm. J Biol Chem. 2018 Nov 30;293(48):18736-18745. doi: 10.1074/jbc.TM118.003337. Epub 2018 Oct 17. J Biol Chem. 2018. PMID: 30333229 Free PMC article. Review.
Dual inhibitors of LSD1 and spermine oxidase.
Holshouser S, Dunworth M, Murray-Stewart T, Peterson YK, Burger P, Kirkpatrick J, Chen HH, Casero RA Jr, Woster PM. Holshouser S, et al. Among authors: woster pm. Medchemcomm. 2019 Feb 8;10(5):778-790. doi: 10.1039/c8md00610e. eCollection 2019 May 1. Medchemcomm. 2019. PMID: 31191868 Free PMC article.
125 results