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Cold-Induced Lipoprotein Clearance in Cyp7b1-Deficient Mice.
Evangelakos I, Kuhl A, Baguhl M, Schlein C, John C, Rohde JK, Heine M, Heeren J, Worthmann A. Evangelakos I, et al. Among authors: worthmann a. Front Cell Dev Biol. 2022 Apr 11;10:836741. doi: 10.3389/fcell.2022.836741. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35478959 Free PMC article.
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development.
Berbée JF, Boon MR, Khedoe PP, Bartelt A, Schlein C, Worthmann A, Kooijman S, Hoeke G, Mol IM, John C, Jung C, Vazirpanah N, Brouwers LP, Gordts PL, Esko JD, Hiemstra PS, Havekes LM, Scheja L, Heeren J, Rensen PC. Berbée JF, et al. Among authors: worthmann a. Nat Commun. 2015 Mar 10;6:6356. doi: 10.1038/ncomms7356. Nat Commun. 2015. PMID: 25754609 Free PMC article.
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport.
Bartelt A, John C, Schaltenberg N, Berbée JFP, Worthmann A, Cherradi ML, Schlein C, Piepenburg J, Boon MR, Rinninger F, Heine M, Toedter K, Niemeier A, Nilsson SK, Fischer M, Wijers SL, van Marken Lichtenbelt W, Scheja L, Rensen PCN, Heeren J. Bartelt A, et al. Among authors: worthmann a. Nat Commun. 2017 Apr 19;8:15010. doi: 10.1038/ncomms15010. Nat Commun. 2017. PMID: 28422089 Free PMC article. Clinical Trial.
Metabolic Circuit Involving Free Fatty Acids, microRNA 122, and Triglyceride Synthesis in Liver and Muscle Tissues.
Chai C, Rivkin M, Berkovits L, Simerzin A, Zorde-Khvalevsky E, Rosenberg N, Klein S, Yaish D, Durst R, Shpitzen S, Udi S, Tam J, Heeren J, Worthmann A, Schramm C, Kluwe J, Ravid R, Hornstein E, Giladi H, Galun E. Chai C, et al. Among authors: worthmann a. Gastroenterology. 2017 Nov;153(5):1404-1415. doi: 10.1053/j.gastro.2017.08.013. Epub 2017 Aug 9. Gastroenterology. 2017. PMID: 28802563
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Krasemann S, Madore C, Cialic R, Baufeld C, Calcagno N, El Fatimy R, Beckers L, O'Loughlin E, Xu Y, Fanek Z, Greco DJ, Smith ST, Tweet G, Humulock Z, Zrzavy T, Conde-Sanroman P, Gacias M, Weng Z, Chen H, Tjon E, Mazaheri F, Hartmann K, Madi A, Ulrich JD, Glatzel M, Worthmann A, Heeren J, Budnik B, Lemere C, Ikezu T, Heppner FL, Litvak V, Holtzman DM, Lassmann H, Weiner HL, Ochando J, Haass C, Butovsky O. Krasemann S, et al. Among authors: worthmann a. Immunity. 2017 Sep 19;47(3):566-581.e9. doi: 10.1016/j.immuni.2017.08.008. Immunity. 2017. PMID: 28930663 Free PMC article.
Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation.
Fischer AW, Jaeckstein MY, Gottschling K, Heine M, Sass F, Mangels N, Schlein C, Worthmann A, Bruns OT, Yuan Y, Zhu H, Chen O, Ittrich H, Nilsson SK, Stefanicka P, Ukropec J, Balaz M, Dong H, Sun W, Reimer R, Scheja L, Heeren J. Fischer AW, et al. Among authors: worthmann a. Cell Metab. 2021 Mar 2;33(3):547-564.e7. doi: 10.1016/j.cmet.2020.12.001. Epub 2020 Dec 22. Cell Metab. 2021. PMID: 33357458 Free article.
26 results