Wootten D - Search Results

1

Walsh MA, Nannenga BL, Gonen T, Sexton PM, Wootten D, Chiu W, Sun F, Carragher B, Potter CS, Agard D, Burley SK. Walsh MA, et al. Among authors: wootten d. Structure. 2023 Nov 2;31(11):1284-1288. doi: 10.1016/j.str.2023.10.002. Structure. 2023. PMID: 37922863

2

Receptor activity modifying proteins (RAMPs) interact with the VPAC2 receptor and CRF1 receptors and modulate their function.

Wootten D, Lindmark H, Kadmiel M, Willcockson H, Caron KM, Barwell J, Drmota T, Poyner DR. Wootten D, et al. Br J Pharmacol. 2013 Feb;168(4):822-34. doi: 10.1111/j.1476-5381.2012.02202.x. Br J Pharmacol. 2013. PMID: 22946657 Free PMC article.

3

Extracellular loops and ligand binding to a subfamily of Family A G-protein-coupled receptors.

Wheatley M, Simms J, Hawtin SR, Wesley VJ, Wootten D, Conner M, Lawson Z, Conner AC, Baker A, Cashmore Y, Kendrick R, Parslow RA. Wheatley M, et al. Among authors: wootten d. Biochem Soc Trans. 2007 Aug;35(Pt 4):717-20. doi: 10.1042/BST0350717. Biochem Soc Trans. 2007. PMID: 17635132 Review.

4

Structural Basis for Allosteric Modulation of Class B G Protein-Coupled Receptors.

Wootten D, Miller LJ. Wootten D, et al. Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:89-107. doi: 10.1146/annurev-pharmtox-010919-023301. Epub 2019 Aug 27. Annu Rev Pharmacol Toxicol. 2020. PMID: 31454292 Free PMC article. Review.

5

Lifting the lid on GPCRs: the role of extracellular loops.

Wheatley M, Wootten D, Conner MT, Simms J, Kendrick R, Logan RT, Poyner DR, Barwell J. Wheatley M, et al. Among authors: wootten d. Br J Pharmacol. 2012 Mar;165(6):1688-1703. doi: 10.1111/j.1476-5381.2011.01629.x. Br J Pharmacol. 2012. PMID: 21864311 Free PMC article. Review.

6

Agonist-specific requirement for a glutamate in transmembrane helix 1 of the oxytocin receptor.

Wootten DL, Simms J, Massoura AJ, Trim JE, Wheatley M. Wootten DL, et al. Mol Cell Endocrinol. 2011 Feb 10;333(1):20-7. doi: 10.1016/j.mce.2010.11.029. Epub 2010 Dec 3. Mol Cell Endocrinol. 2011. PMID: 21130837

7

Diverse functional motifs within the three intracellular loops of the CGRP1 receptor.

Conner AC, Simms J, Conner MT, Wootten DL, Wheatley M, Poyner DR. Conner AC, et al. Biochemistry. 2006 Oct 31;45(43):12976-85. doi: 10.1021/bi0615801. Biochemistry. 2006. PMID: 17059214

8

Consequences of splice variation on Secretin family G protein-coupled receptor function.

Furness SG, Wootten D, Christopoulos A, Sexton PM. Furness SG, et al. Among authors: wootten d. Br J Pharmacol. 2012 May;166(1):98-109. doi: 10.1111/j.1476-5381.2011.01571.x. Br J Pharmacol. 2012. PMID: 21718310 Free PMC article. Review.

9

Polar transmembrane interactions drive formation of ligand-specific and signal pathway-biased family B G protein-coupled receptor conformations.

Wootten D, Simms J, Miller LJ, Christopoulos A, Sexton PM. Wootten D, et al. Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5211-6. doi: 10.1073/pnas.1221585110. Epub 2013 Mar 11. Proc Natl Acad Sci U S A. 2013. PMID: 23479653 Free PMC article.

10

Structural biology: meet the B family.

Sexton PM, Wootten D. Sexton PM, et al. Among authors: wootten d. Nature. 2013 Jul 25;499(7459):417-8. doi: 10.1038/nature12413. Epub 2013 Jul 17. Nature. 2013. PMID: 23863934 No abstract available.

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