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Real-time analysis of the binding of fluorescent VEGF165a to VEGFR2 in living cells: Effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor complexes.
Kilpatrick LE, Friedman-Ohana R, Alcobia DC, Riching K, Peach CJ, Wheal AJ, Briddon SJ, Robers MB, Zimmerman K, Machleidt T, Wood KV, Woolard J, Hill SJ. Kilpatrick LE, et al. Among authors: woolard j. Biochem Pharmacol. 2017 Jul 15;136:62-75. doi: 10.1016/j.bcp.2017.04.006. Epub 2017 Apr 7. Biochem Pharmacol. 2017. PMID: 28392095 Free PMC article.
Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease.
Baker JG, Gardiner SM, Woolard J, Fromont C, Jadhav GP, Mistry SN, Thompson KSJ, Kellam B, Hill SJ, Fischer PM. Baker JG, et al. Among authors: woolard j. FASEB J. 2017 Jul;31(7):3150-3166. doi: 10.1096/fj.201601305R. Epub 2017 Apr 11. FASEB J. 2017. PMID: 28400472 Free PMC article.
They potentially offer a truly cardioselective beta-blocker therapy for the large number of patients with heart and respiratory or peripheral vascular comorbidities.-Baker, J. G., Gardiner, S. M., Woolard, J., Fromont, C., Jadhav, G. P., Mistry, S. N., Thomps …
They potentially offer a truly cardioselective beta-blocker therapy for the large number of patients with heart and respiratory or periphera …
A monoclonal antibody raised against a thermo-stabilised β1-adrenoceptor interacts with extracellular loop 2 and acts as a negative allosteric modulator of a sub-set of β1-adrenoceptors expressed in stable cell lines.
Soave M, Cseke G, Hutchings CJ, Brown AJH, Woolard J, Hill SJ. Soave M, et al. Among authors: woolard j. Biochem Pharmacol. 2018 Jan;147:38-54. doi: 10.1016/j.bcp.2017.10.015. Epub 2017 Nov 2. Biochem Pharmacol. 2018. PMID: 29102678 Free PMC article.
62 results