Wood NT - Search Results

1

Deubiquitinating enzyme amino acid profiling reveals a class of ubiquitin esterases.

De Cesare V, Carbajo Lopez D, Mabbitt PD, Fletcher AJ, Soetens M, Antico O, Wood NT, Virdee S. De Cesare V, et al. Among authors: wood nt. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2006947118. doi: 10.1073/pnas.2006947118. Proc Natl Acad Sci U S A. 2021. PMID: 33479176 Free PMC article.

2

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry.

Ritorto MS, Ewan R, Perez-Oliva AB, Knebel A, Buhrlage SJ, Wightman M, Kelly SM, Wood NT, Virdee S, Gray NS, Morrice NA, Alessi DR, Trost M. Ritorto MS, et al. Among authors: wood nt. Nat Commun. 2014 Aug 27;5:4763. doi: 10.1038/ncomms5763. Nat Commun. 2014. PMID: 25159004 Free PMC article.

3

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation.

Pao KC, Stanley M, Han C, Lai YC, Murphy P, Balk K, Wood NT, Corti O, Corvol JC, Muqit MM, Virdee S. Pao KC, et al. Among authors: wood nt. Nat Chem Biol. 2016 May;12(5):324-31. doi: 10.1038/nchembio.2045. Epub 2016 Mar 7. Nat Chem Biol. 2016. PMID: 26928937 Free PMC article.

4

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

Pao KC, Wood NT, Knebel A, Rafie K, Stanley M, Mabbitt PD, Sundaramoorthy R, Hofmann K, van Aalten DMF, Virdee S. Pao KC, et al. Among authors: wood nt. Nature. 2018 Apr;556(7701):381-385. doi: 10.1038/s41586-018-0026-1. Epub 2018 Apr 11. Nature. 2018. PMID: 29643511 Free article.

5

Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity.

Mabbitt PD, Loreto A, Déry MA, Fletcher AJ, Stanley M, Pao KC, Wood NT, Coleman MP, Virdee S. Mabbitt PD, et al. Among authors: wood nt. Nat Chem Biol. 2020 Nov;16(11):1227-1236. doi: 10.1038/s41589-020-0598-6. Epub 2020 Aug 3. Nat Chem Biol. 2020. PMID: 32747811 Free PMC article.

6

UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4.

Barnsby-Greer L, Mabbitt PD, Dery MA, Squair DR, Wood NT, Lamoliatte F, Lange SM, Virdee S. Barnsby-Greer L, et al. Among authors: wood nt. Nat Struct Mol Biol. 2024 Feb;31(2):351-363. doi: 10.1038/s41594-023-01192-4. Epub 2024 Jan 5. Nat Struct Mol Biol. 2024. PMID: 38182926 Free PMC article.

7

HOIL-1 ubiquitin ligase activity targets unbranched glucosaccharides and is required to prevent polyglucosan accumulation.

Kelsall IR, McCrory EH, Xu Y, Scudamore CL, Nanda SK, Mancebo-Gamella P, Wood NT, Knebel A, Matthews SJ, Cohen P. Kelsall IR, et al. Among authors: wood nt. EMBO J. 2022 Apr 19;41(8):e109700. doi: 10.15252/embj.2021109700. Epub 2022 Mar 11. EMBO J. 2022. PMID: 35274759 Free PMC article.

8

ALPK1 mutants causing ROSAH syndrome or Spiradenoma are activated by human nucleotide sugars.

Snelling T, Saalfrank A, Wood NT, Cohen P. Snelling T, et al. Among authors: wood nt. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2313148120. doi: 10.1073/pnas.2313148120. Epub 2023 Dec 7. Proc Natl Acad Sci U S A. 2023. PMID: 38060563 Free PMC article.

9

The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction.

Ohta A, Schumacher FR, Mehellou Y, Johnson C, Knebel A, Macartney TJ, Wood NT, Alessi DR, Kurz T. Ohta A, et al. Among authors: wood nt. Biochem J. 2013 Apr 1;451(1):111-22. doi: 10.1042/BJ20121903. Biochem J. 2013. PMID: 23387299 Free PMC article.

10

VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase.

Baron Y, Pedrioli PG, Tyagi K, Johnson C, Wood NT, Fountaine D, Wightman M, Alexandru G. Baron Y, et al. Among authors: wood nt. BMC Biol. 2014 May 29;12:39. doi: 10.1186/1741-7007-12-39. BMC Biol. 2014. PMID: 24885147 Free PMC article.

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