Wong PC - Search Results

1

Pathological Tau transmission initiated by binding lymphocyte-activation gene 3.

Chen C, Kumbhar R, Wang H, Yang X, Gadhave K, Rastegar C, Kimura Y, Behensky A, Katakam S, Jeong D, Wang L, Wang A, Chen R, Zhang S, Jin L, Workman CJ, Vignali DAA, Pletinkova O, Nauen DW, Wong PC, Troncoso JC, Ying M, Dawson VL, Dawson TM, Mao X. Chen C, et al. Among authors: wong pc. bioRxiv [Preprint]. 2023 May 17:2023.05.16.541015. doi: 10.1101/2023.05.16.541015. bioRxiv. 2023. PMID: 37293032 Free PMC article. Updated. Preprint.

2

Stroke outcome in double-mutant antioxidant transgenic mice.

Sampei K, Mandir AS, Asano Y, Wong PC, Traystman RJ, Dawson VL, Dawson TM, Hurn PD. Sampei K, et al. Among authors: wong pc. Stroke. 2000 Nov;31(11):2685-91. doi: 10.1161/01.str.31.11.2685. Stroke. 2000. PMID: 11062295

3

Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation.

Wu J, Petralia RS, Kurushima H, Patel H, Jung MY, Volk L, Chowdhury S, Shepherd JD, Dehoff M, Li Y, Kuhl D, Huganir RL, Price DL, Scannevin R, Troncoso JC, Wong PC, Worley PF. Wu J, et al. Among authors: wong pc. Cell. 2011 Oct 28;147(3):615-28. doi: 10.1016/j.cell.2011.09.036. Cell. 2011. PMID: 22036569 Free PMC article.

4

Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice.

LaClair KD, Manaye KF, Lee DL, Allard JS, Savonenko AV, Troncoso JC, Wong PC. LaClair KD, et al. Among authors: wong pc. Mol Neurodegener. 2013 Jun 13;8:18. doi: 10.1186/1750-1326-8-18. Mol Neurodegener. 2013. PMID: 23764200 Free PMC article.

5

TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD.

Ling JP, Pletnikova O, Troncoso JC, Wong PC. Ling JP, et al. Among authors: wong pc. Science. 2015 Aug 7;349(6248):650-5. doi: 10.1126/science.aab0983. Science. 2015. PMID: 26250685 Free PMC article.

6

Cryptic exon incorporation occurs in Alzheimer's brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43.

Sun M, Bell W, LaClair KD, Ling JP, Han H, Kageyama Y, Pletnikova O, Troncoso JC, Wong PC, Chen LL. Sun M, et al. Among authors: wong pc. Acta Neuropathol. 2017 Jun;133(6):923-931. doi: 10.1007/s00401-017-1701-2. Epub 2017 Mar 22. Acta Neuropathol. 2017. PMID: 28332094 Free PMC article.

7

Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes.

Kim DW, Tu KJ, Wei A, Lau AJ, Gonzalez-Gil A, Cao T, Braunstein K, Ling JP, Troncoso JC, Wong PC, Blackshaw S, Schnaar RL, Li T. Kim DW, et al. Among authors: wong pc. Mol Neurodegener. 2022 Dec 17;17(1):83. doi: 10.1186/s13024-022-00589-x. Mol Neurodegener. 2022. PMID: 36536457 Free PMC article.

8

Elevated nuclear TDP-43 induces constitutive exon skipping.

Carmen-Orozco RP, Tsao W, Ye Y, Sinha IR, Chang K, Trinh V, Chung W, Bowden K, Troncoso JC, Blackshaw S, Hayes LR, Sun S, Wong PC, Ling JP. Carmen-Orozco RP, et al. Among authors: wong pc. bioRxiv [Preprint]. 2023 May 12:2023.05.11.540291. doi: 10.1101/2023.05.11.540291. bioRxiv. 2023. PMID: 37215013 Free PMC article. Preprint.

9

Loss of TDP-43 splicing repression occurs early in the aging population and is associated with Alzheimer's disease neuropathologic changes and cognitive decline.

Chang K, Ling JP, Redding-Ochoa J, An Y, Li L, Dean SA, Blanchard TG, Pylyukh T, Barrett A, Irwin KE, Moghekar A, Resnick SM, Wong PC, Troncoso JC. Chang K, et al. Among authors: wong pc. Acta Neuropathol. 2023 Dec 22;147(1):4. doi: 10.1007/s00401-023-02653-2. Acta Neuropathol. 2023. PMID: 38133681

10

The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model.

Li T, Braunstein KE, Zhang J, Lau A, Sibener L, Deeble C, Wong PC. Li T, et al. Among authors: wong pc. Nat Commun. 2016 Jul 4;7:12082. doi: 10.1038/ncomms12082. Nat Commun. 2016. PMID: 27373369 Free PMC article.

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