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Chronic sympathetic driven hypertension promotes atherosclerosis by enhancing hematopoiesis.
Al-Sharea A, Lee MKS, Whillas A, Michell DL, Shihata WA, Nicholls AJ, Cooney OD, Kraakman MJ, Veiga CB, Jefferis AM, Jackson K, Nagareddy PR, Lambert G, Wong CHY, Andrews KL, Head GA, Chin-Dusting J, Murphy AJ. Al-Sharea A, et al. Among authors: wong chy. Haematologica. 2019 Mar;104(3):456-467. doi: 10.3324/haematol.2018.192898. Epub 2018 Oct 25. Haematologica. 2019. PMID: 30361420 Free PMC article.
Advanced age promotes colonic dysfunction and gut-derived lung infection after stroke.
Wen SW, Shim R, Ho L, Wanrooy BJ, Srikhanta YN, Prame Kumar K, Nicholls AJ, Shen SJ, Sepehrizadeh T, de Veer M, Srikanth VK, Ma H, Phan TG, Lyras D, Wong CHY. Wen SW, et al. Among authors: wong chy. Aging Cell. 2019 Oct;18(5):e12980. doi: 10.1111/acel.12980. Epub 2019 Jun 14. Aging Cell. 2019. PMID: 31199577 Free PMC article.
Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation.
Selvadurai MV, Moon MJ, Mountford SJ, Ma X, Zheng Z, Jennings IG, Setiabakti NM, Iman RP, Brazilek RJ, Z Abidin NA, Chicanne G, Severin S, Nicholls AJ, Wong CHY, Rinckel JY, Eckly A, Gachet C, Nesbitt WS, Thompson PE, Hamilton JR. Selvadurai MV, et al. Among authors: wong chy. Sci Transl Med. 2020 Jul 22;12(553):eaar8430. doi: 10.1126/scitranslmed.aar8430. Sci Transl Med. 2020. PMID: 32718993
Aging- and vascular-related pathologies.
Wen SW, Wong CHY. Wen SW, et al. Among authors: wong chy. Microcirculation. 2019 Feb;26(2):e12463. doi: 10.1111/micc.12463. Epub 2018 Jun 19. Microcirculation. 2019. PMID: 29846990 Review.
83 results