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DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency.
Taguchi J, Shibata H, Kabata M, Kato M, Fukuda K, Tanaka A, Ohta S, Ukai T, Mitsunaga K, Yamada Y, Nagaoka SI, Yamazawa S, Ohnishi K, Woltjen K, Ushiku T, Ozawa M, Saitou M, Shinkai Y, Yamamoto T, Yamada Y. Taguchi J, et al. Among authors: woltjen k. Nat Commun. 2021 Aug 19;12(1):5041. doi: 10.1038/s41467-021-25249-4. Nat Commun. 2021. PMID: 34413299 Free PMC article.
Microhomology-assisted scarless genome editing in human iPSCs.
Kim SI, Matsumoto T, Kagawa H, Nakamura M, Hirohata R, Ueno A, Ohishi M, Sakuma T, Soga T, Yamamoto T, Woltjen K. Kim SI, et al. Among authors: woltjen k. Nat Commun. 2018 Mar 5;9(1):939. doi: 10.1038/s41467-018-03044-y. Nat Commun. 2018. PMID: 29507284 Free PMC article.
In vivo reprogramming drives Kras-induced cancer development.
Shibata H, Komura S, Yamada Y, Sankoda N, Tanaka A, Ukai T, Kabata M, Sakurai S, Kuze B, Woltjen K, Haga H, Ito Y, Kawaguchi Y, Yamamoto T, Yamada Y. Shibata H, et al. Among authors: woltjen k. Nat Commun. 2018 May 25;9(1):2081. doi: 10.1038/s41467-018-04449-5. Nat Commun. 2018. PMID: 29802314 Free PMC article.
Cell-type dependent enhancer binding of the EWS/ATF1 fusion gene in clear cell sarcomas.
Komura S, Ito K, Ohta S, Ukai T, Kabata M, Itakura F, Semi K, Matsuda Y, Hashimoto K, Shibata H, Sone M, Jo N, Sekiguchi K, Ohno T, Akiyama H, Shimizu K, Woltjen K, Ozawa M, Toguchida J, Yamamoto T, Yamada Y. Komura S, et al. Among authors: woltjen k. Nat Commun. 2019 Sep 5;10(1):3999. doi: 10.1038/s41467-019-11745-1. Nat Commun. 2019. PMID: 31488818 Free PMC article.
72 results