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Halogen-Aromatic π Interactions Modulate Inhibitor Residence Times.
Angew Chem Int Ed Engl. 2018 Jun 11;57(24):7220-7224. doi: 10.1002/anie.201801666. Epub 2018 May 9.
Angew Chem Int Ed Engl. 2018.
PMID: 29601130
Free PMC article.
Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib.
Mathea S, Abdul Azeez KR, Salah E, Tallant C, Wolfreys F, Konietzny R, Fischer R, Lou HJ, Brennan PE, Schnapp G, Pautsch A, Kessler BM, Turk BE, Knapp S.
Mathea S, et al. Among authors: wolfreys f.
ACS Chem Biol. 2016 Jun 17;11(6):1595-602. doi: 10.1021/acschembio.6b00043. Epub 2016 Mar 31.
ACS Chem Biol. 2016.
PMID: 26999302
Free PMC article.
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Novel Mechanisms Guide Innovative Molecular-Based Therapeutic Strategies for Fuchs Endothelial Corneal Dystrophy.
Chan MF, Pan P, Wolfreys FD.
Chan MF, et al. Among authors: wolfreys fd.
Cornea. 2023 Aug 1;42(8):929-933. doi: 10.1097/ICO.0000000000003292. Epub 2023 Jun 13.
Cornea. 2023.
PMID: 37318135
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Characterization of Recruited Mononuclear Phagocytes following Corneal Chemical Injury.
Lamy R, Wolf M, Bispo C, Clay SM, Zheng S, Wolfreys F, Pan P, Chan MF.
Lamy R, et al. Among authors: wolfreys f.
Int J Mol Sci. 2022 Feb 25;23(5):2574. doi: 10.3390/ijms23052574.
Int J Mol Sci. 2022.
PMID: 35269717
Free PMC article.
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P2RY8 variants in lupus patients uncover a role for the receptor in immunological tolerance.
He Y, Gallman AE, Xie C, Shen Q, Ma J, Wolfreys FD, Sandy M, Arsov T, Wu X, Qin Y, Zhang P, Jiang S, Stanley M, Wu P, Tan J, Ding H, Xue H, Chen W, Xu J, Criswell LA, Nititham J, Adamski M, Kitching AR, Cook MC, Cao L, Shen N, Cyster JG, Vinuesa CG.
He Y, et al. Among authors: wolfreys fd.
J Exp Med. 2022 Jan 3;219(1):e20211004. doi: 10.1084/jem.20211004. Epub 2021 Dec 10.
J Exp Med. 2022.
PMID: 34889940
Free PMC article.
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Abcc1 and Ggt5 support lymphocyte guidance through export and catabolism of S-geranylgeranyl-l-glutathione.
Gallman AE, Wolfreys FD, Nguyen DN, Sandy M, Xu Y, An J, Li Z, Marson A, Lu E, Cyster JG.
Gallman AE, et al. Among authors: wolfreys fd.
Sci Immunol. 2021 Jun 4;6(60):eabg1101. doi: 10.1126/sciimmunol.abg1101.
Sci Immunol. 2021.
PMID: 34088745
Free PMC article.
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S-Geranylgeranyl-L-glutathione is a ligand for human B cell-confinement receptor P2RY8.
Lu E, Wolfreys FD, Muppidi JR, Xu Y, Cyster JG.
Lu E, et al. Among authors: wolfreys fd.
Nature. 2019 Mar;567(7747):244-248. doi: 10.1038/s41586-019-1003-z. Epub 2019 Mar 6.
Nature. 2019.
PMID: 30842656
Free PMC article.
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