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Challenges in inhaled product development and opportunities for open innovation.
Forbes B, Asgharian B, Dailey LA, Ferguson D, Gerde P, Gumbleton M, Gustavsson L, Hardy C, Hassall D, Jones R, Lock R, Maas J, McGovern T, Pitcairn GR, Somers G, Wolff RK. Forbes B, et al. Among authors: wolff rk. Adv Drug Deliv Rev. 2011 Jan-Feb;63(1-2):69-87. doi: 10.1016/j.addr.2010.11.004. Epub 2010 Dec 6. Adv Drug Deliv Rev. 2011. PMID: 21144875 Review.
Foreign particles testing in orally inhaled and nasal drug products.
Blanchard J, Coleman J, Hayling CD, Ghaderi R, Haeberlin B, Hart J, Jensen S, Malcolmson R, Mittelman S, Nagao LM, Sekulic S, Snodgrass-Pilla C, Sundahl M, Thompson G, Wolff R; International Pharmaceutical Aerosol Consortium on Regulation; Science Foreign Particles Working Group. Blanchard J, et al. Pharm Res. 2004 Dec;21(12):2137-47. doi: 10.1007/s11095-004-7665-7. Pharm Res. 2004. PMID: 15648243 Review.
Best practices for managing quality and safety of foreign particles in orally inhaled and nasal drug products, and an evaluation of clinical relevance.
Blanchard J, Coleman J, Crim C, Dabreu-Hayling C, Fries L, Ghaderi R, Haeberlin B, Malcolmson R, Mittelman S, Nagao L, Saracovan I, Shtohryn L, Snodgrass-Pilla C, Sundahl M, Wolff R. Blanchard J, et al. Pharm Res. 2007 Mar;24(3):471-9. doi: 10.1007/s11095-006-9172-5. Pharm Res. 2007. PMID: 17252189 No abstract available.
Practical Considerations in Dose Extrapolation from Animals to Humans.
Hickey AJ, Maloney SE, Kuehl PJ, Phillips JE, Wolff RK. Hickey AJ, et al. Among authors: wolff rk. J Aerosol Med Pulm Drug Deliv. 2024 Apr;37(2):77-89. doi: 10.1089/jamp.2023.0041. Epub 2024 Jan 17. J Aerosol Med Pulm Drug Deliv. 2024. PMID: 38237032 Review.
ARF6-dependent endocytic trafficking of the Interferon-γ receptor drives adaptive immune resistance in cancer.
Wee Y, Wang J, Wilson EC, Rich CP, Rogers A, Tong Z, DeGroot E, Gopal YNV, Davies MA, Ekiz HA, Tay JKH, Stubben C, Boucher KM, Oviedo JM, Fairfax KC, Williams MA, Holmen SL, Wolff RK, Grossmann AH. Wee Y, et al. Among authors: wolff rk. bioRxiv [Preprint]. 2023 Oct 2:2023.09.29.560199. doi: 10.1101/2023.09.29.560199. bioRxiv. 2023. PMID: 37873189 Free PMC article. Preprint.
Inhalation Pharmacodynamics.
Wolff RK. Wolff RK. J Aerosol Med Pulm Drug Deliv. 2023 Oct;36(5):275-280. doi: 10.1089/jamp.2023.29092.rkw. J Aerosol Med Pulm Drug Deliv. 2023. PMID: 37851976 Review.
Energy homeostasis genes modify the association between serum concentrations of IGF-1 and IGFBP-3 and breast cancer risk.
Rodríguez-Valentín R, Torres-Mejía G, Martínez-Matsushita L, Angeles-Llerenas A, Gómez-Flores-Ramos L, Wolff RK, Baumgartner KB, Hines LM, Ziv E, Flores-Luna L, Sánchez-Zamorano LM, Ortiz-Panozo E, Slattery ML. Rodríguez-Valentín R, et al. Among authors: wolff rk. Sci Rep. 2022 Feb 3;12(1):1837. doi: 10.1038/s41598-022-05496-1. Sci Rep. 2022. PMID: 35115550 Free PMC article.
241 results