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Failure of downregulation of survivin following neoadjuvant radiochemotherapy in rectal cancer is associated with distant metastases and shortened survival.
Sprenger T, Rödel F, Beissbarth T, Conradi LC, Rothe H, Homayounfar K, Wolff HA, Ghadimi BM, Yildirim M, Becker H, Rödel C, Liersch T. Sprenger T, et al. Among authors: wolff ha. Clin Cancer Res. 2011 Mar 15;17(6):1623-31. doi: 10.1158/1078-0432.CCR-10-2592. Epub 2010 Nov 30. Clin Cancer Res. 2011. PMID: 21118954 Clinical Trial.
A putatively functional haplotype in the gene encoding transforming growth factor beta-1 as a potential biomarker for radiosensitivity.
Schirmer MA, Brockmöller J, Rave-Fränk M, Virsik P, Wilken B, Kühnle E, Campean R, Hoffmann AO, Müller K, Goetze RG, Neumann M, Janke JH, Nasser F, Wolff HA, Ghadimi BM, Schmidberger H, Hess CF, Christiansen H, Hille A. Schirmer MA, et al. Among authors: wolff ha. Int J Radiat Oncol Biol Phys. 2011 Mar 1;79(3):866-74. doi: 10.1016/j.ijrobp.2010.08.040. Epub 2010 Dec 22. Int J Radiat Oncol Biol Phys. 2011. PMID: 21183289
Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy.
Kendziorra E, Ahlborn K, Spitzner M, Rave-Fränk M, Emons G, Gaedcke J, Kramer F, Wolff HA, Becker H, Beissbarth T, Ebner R, Ghadimi BM, Pukrop T, Ried T, Grade M. Kendziorra E, et al. Among authors: wolff ha. Carcinogenesis. 2011 Dec;32(12):1824-31. doi: 10.1093/carcin/bgr222. Epub 2011 Oct 8. Carcinogenesis. 2011. PMID: 21983179 Free PMC article.
Enrichment of CD133-expressing cells in rectal cancers treated with preoperative radiochemotherapy is an independent marker for metastasis and survival.
Sprenger T, Conradi LC, Beissbarth T, Ermert H, Homayounfar K, Middel P, Rüschoff J, Wolff HA, Schüler P, Ghadimi BM, Rödel C, Becker H, Rödel F, Liersch T. Sprenger T, et al. Among authors: wolff ha. Cancer. 2013 Jan 1;119(1):26-35. doi: 10.1002/cncr.27703. Epub 2012 Jun 26. Cancer. 2013. PMID: 22736392 Free article. Clinical Trial.
Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g.
Salendo J, Spitzner M, Kramer F, Zhang X, Jo P, Wolff HA, Kitz J, Kaulfuß S, Beißbarth T, Dobbelstein M, Ghadimi M, Grade M, Gaedcke J. Salendo J, et al. Among authors: wolff ha. Radiother Oncol. 2013 Sep;108(3):451-7. doi: 10.1016/j.radonc.2013.06.032. Epub 2013 Aug 7. Radiother Oncol. 2013. PMID: 23932154
108 results