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Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.
Webby CJ, Wolf A, Gromak N, Dreger M, Kramer H, Kessler B, Nielsen ML, Schmitz C, Butler DS, Yates JR 3rd, Delahunty CM, Hahn P, Lengeling A, Mann M, Proudfoot NJ, Schofield CJ, Böttger A. Webby CJ, et al. Among authors: wolf a. Science. 2009 Jul 3;325(5936):90-3. doi: 10.1126/science.1175865. Science. 2009. PMID: 19574390 Free article.
A photoreactive small-molecule probe for 2-oxoglutarate oxygenases.
Rotili D, Altun M, Kawamura A, Wolf A, Fischer R, Leung IKH, Mackeen MM, Tian YM, Ratcliffe PJ, Mai A, Kessler BM, Schofield CJ. Rotili D, et al. Among authors: wolf a. Chem Biol. 2011 May 27;18(5):642-654. doi: 10.1016/j.chembiol.2011.03.007. Chem Biol. 2011. PMID: 21609845 Free PMC article.
Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans.
Ge W, Wolf A, Feng T, Ho CH, Sekirnik R, Zayer A, Granatino N, Cockman ME, Loenarz C, Loik ND, Hardy AP, Claridge TDW, Hamed RB, Chowdhury R, Gong L, Robinson CV, Trudgian DC, Jiang M, Mackeen MM, Mccullagh JS, Gordiyenko Y, Thalhammer A, Yamamoto A, Yang M, Liu-Yi P, Zhang Z, Schmidt-Zachmann M, Kessler BM, Ratcliffe PJ, Preston GM, Coleman ML, Schofield CJ. Ge W, et al. Among authors: wolf a. Nat Chem Biol. 2012 Dec;8(12):960-962. doi: 10.1038/nchembio.1093. Epub 2012 Oct 28. Nat Chem Biol. 2012. PMID: 23103944 Free PMC article.
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy.
Loenarz C, Sekirnik R, Thalhammer A, Ge W, Spivakovsky E, Mackeen MM, McDonough MA, Cockman ME, Kessler BM, Ratcliffe PJ, Wolf A, Schofield CJ. Loenarz C, et al. Among authors: wolf a. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4019-24. doi: 10.1073/pnas.1311750111. Epub 2014 Feb 18. Proc Natl Acad Sci U S A. 2014. PMID: 24550462 Free PMC article.
3,252 results