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Pharmacophore-based discovery of a novel cytosolic phospholipase A(2)α inhibitor.
Noha SM, Jazzar B, Kuehnl S, Rollinger JM, Stuppner H, Schaible AM, Werz O, Wolber G, Schuster D. Noha SM, et al. Among authors: wolber g. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1202-7. doi: 10.1016/j.bmcl.2011.11.093. Epub 2011 Nov 30. Bioorg Med Chem Lett. 2012. PMID: 22192589 Free PMC article.
New 4-[(5-arylidene-2-arylimino-4-oxo-3-thiazolidinyl)methyl]benzoic acids active as protein tyrosine phosphatase inhibitors endowed with insulinomimetic effect on mouse C2C12 skeletal muscle cells.
Ottanà R, Maccari R, Amuso S, Wolber G, Schuster D, Herdlinger S, Manao G, Camici G, Paoli P. Ottanà R, et al. Among authors: wolber g. Eur J Med Chem. 2012 Apr;50:332-43. doi: 10.1016/j.ejmech.2012.02.012. Epub 2012 Feb 21. Eur J Med Chem. 2012. PMID: 22381357
Synthesis, biological activity and structure-activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells.
Ottanà R, Maccari R, Mortier J, Caselli A, Amuso S, Camici G, Rotondo A, Wolber G, Paoli P. Ottanà R, et al. Among authors: wolber g. Eur J Med Chem. 2014 Jan;71:112-27. doi: 10.1016/j.ejmech.2013.11.001. Epub 2013 Nov 11. Eur J Med Chem. 2014. PMID: 24287560
212 results