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Fenretinide corrects newly found ceramide deficiency in cystic fibrosis.
Guilbault C, De Sanctis JB, Wojewodka G, Saeed Z, Lachance C, Skinner TA, Vilela RM, Kubow S, Lands LC, Hajduch M, Matouk E, Radzioch D. Guilbault C, et al. Among authors: wojewodka g. Am J Respir Cell Mol Biol. 2008 Jan;38(1):47-56. doi: 10.1165/rcmb.2007-0036OC. Epub 2007 Jul 26. Am J Respir Cell Mol Biol. 2008. PMID: 17656682
Fenretinide differentially modulates the levels of long- and very long-chain ceramides by downregulating Cers5 enzyme: evidence from bench to bedside.
Garić D, De Sanctis JB, Wojewodka G, Houle D, Cupri S, Abu-Arish A, Hanrahan JW, Hajduch M, Matouk E, Radzioch D. Garić D, et al. Among authors: wojewodka g. J Mol Med (Berl). 2017 Oct;95(10):1053-1064. doi: 10.1007/s00109-017-1564-y. Epub 2017 Jul 10. J Mol Med (Berl). 2017. PMID: 28695226 Clinical Trial.
Cystic fibrosis-adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses.
LaFayette SL, Houle D, Beaudoin T, Wojewodka G, Radzioch D, Hoffman LR, Burns JL, Dandekar AA, Smalley NE, Chandler JR, Zlosnik JE, Speert DP, Bernier J, Matouk E, Brochiero E, Rousseau S, Nguyen D. LaFayette SL, et al. Among authors: wojewodka g. Sci Adv. 2015 Jul;1(6):e1500199. doi: 10.1126/sciadv.1500199. Epub 2015 Jul 31. Sci Adv. 2015. PMID: 26457326 Free PMC article.
32 results