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Pharmacokinetic/Toxicity Properties of the New Anti-Staphylococcal Lead Compound SK-03-92.
Antibiotics (Basel). 2015 Dec;4(4):617-626. doi: 10.3390/antibiotics4040617. Epub 2015 Nov 24.
Antibiotics (Basel). 2015.
PMID: 26877886
Free PMC article.
Identification of Staphylococcus aureus Cellular Pathways Affected by the Stilbenoid Lead Drug SK-03-92 Using a Microarray.
Schwan WR, Polanowski R, Dunman PM, Medina-Bielski S, Lane M, Rott M, Lipker L, Wescott A, Monte A, Cook JM, Baumann DD, Tiruveedhula VVNPB, Witzigmann CM, Mikel C, Rahman MT.
Schwan WR, et al. Among authors: witzigmann cm.
Antibiotics (Basel). 2017 Sep 11;6(3):17. doi: 10.3390/antibiotics6030017.
Antibiotics (Basel). 2017.
PMID: 28892020
Free PMC article.
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Design and synthesis of novel antimicrobials with activity against Gram-positive bacteria and mycobacterial species, including M. tuberculosis.
Tiruveedhula VV, Witzigmann CM, Verma R, Kabir MS, Rott M, Schwan WR, Medina-Bielski S, Lane M, Close W, Polanowski RL, Sherman D, Monte A, Deschamps JR, Cook JM.
Tiruveedhula VV, et al. Among authors: witzigmann cm.
Bioorg Med Chem. 2013 Dec 15;21(24):7830-40. doi: 10.1016/j.bmc.2013.10.011. Epub 2013 Oct 21.
Bioorg Med Chem. 2013.
PMID: 24200931
Free PMC article.
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Characterization of GABAA receptor ligands with automated patch-clamp using human neurons derived from pluripotent stem cells.
Yuan NY, Poe MM, Witzigmann C, Cook JM, Stafford D, Arnold LA.
Yuan NY, et al.
J Pharmacol Toxicol Methods. 2016 Nov-Dec;82:109-114. doi: 10.1016/j.vascn.2016.08.006. Epub 2016 Aug 18.
J Pharmacol Toxicol Methods. 2016.
PMID: 27544543
Free PMC article.
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Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ-Aminobutyric Acid Type A Receptor (GABAAR) α6 Subtype with Improved Metabolic Stability and Enhanced Bioavailability.
Knutson DE, Kodali R, Divović B, Treven M, Stephen MR, Zahn NM, Dobričić V, Huber AT, Meirelles MA, Verma RS, Wimmer L, Witzigmann C, Arnold LA, Chiou LC, Ernst M, Mihovilovic MD, Savić MM, Sieghart W, Cook JM.
Knutson DE, et al.
J Med Chem. 2018 Mar 22;61(6):2422-2446. doi: 10.1021/acs.jmedchem.7b01664. Epub 2018 Mar 6.
J Med Chem. 2018.
PMID: 29481759
Free PMC article.
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Cerebellar α6 -subunit-containing GABAA receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders.
Chiou LC, Lee HJ, Ernst M, Huang WJ, Chou JF, Chen HL, Mouri A, Chen LC, Treven M, Mamiya T, Fan PC, Knutson DE, Witzigmann C, Cook J, Sieghart W, Nabeshima T.
Chiou LC, et al.
Br J Pharmacol. 2018 Jun;175(12):2414-2427. doi: 10.1111/bph.14198. Epub 2018 May 10.
Br J Pharmacol. 2018.
PMID: 29518821
Free PMC article.
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