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Page 1
Tumor necrosis factor α promotes clonal dominance of KIT D816V+ cells in mastocytosis: role of survivin and impact on prognosis.
Greiner G, Witzeneder N, Klein K, Tangermann S, Kodajova P, Jaeger E, Ratzinger F, Gerner MC, Jawhar M, Baumgartner S, Fruehwirth K, Schmetterer KG, Zuber J, Gleixner KV, Mayerhofer M, Schwarzinger I, Simonitsch-Klupp I, Esterbauer H, Baer C, Walter W, Meggendorfer M, Strassl R, Haferlach T, Hartmann K, Kenner L, Sperr WR, Reiter A, Sexl V, Arock M, Valent P, Hoermann G. Greiner G, et al. Among authors: witzeneder n. Blood. 2024 Mar 14;143(11):1006-1017. doi: 10.1182/blood.2023020515. Blood. 2024. PMID: 38142424
STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway.
Pencik J, Philippe C, Schlederer M, Atas E, Pecoraro M, Grund-Gröschke S, Li WJ, Tracz A, Heidegger I, Lagger S, Trachtová K, Oberhuber M, Heitzer E, Aksoy O, Neubauer HA, Wingelhofer B, Orlova A, Witzeneder N, Dillinger T, Redl E, Greiner G, D'Andrea D, Östman JR, Tangermann S, Hermanova I, Schäfer G, Sternberg F, Pohl EE, Sternberg C, Varady A, Horvath J, Stoiber D, Malcolm TI, Turner SD, Parkes EE, Hantusch B, Egger G, Rose-John S, Poli V, Jain S, Armstrong CWD, Hoermann G, Goffin V, Aberger F, Moriggl R, Carracedo A, McKinney C, Kennedy RD, Klocker H, Speicher MR, Tang DG, Moazzami AA, Heery DM, Hacker M, Kenner L. Pencik J, et al. Among authors: witzeneder n. Mol Cancer. 2023 Aug 12;22(1):133. doi: 10.1186/s12943-023-01825-8. Mol Cancer. 2023. PMID: 37573301 Free PMC article.
Engraftment in NSGSCF mice correlates with the WHO category and prognosis in systemic mastocytosis.
Willmann M, Peter B, Slavnitsch K, Berger D, Witzeneder N, Stefanzl G, Eisenwort G, Ivanov D, Sadovnik I, Hadzijusufovic E, Greiner G, Bernthaler T, Hoermann G, Dahlhoff M, Rülicke T, Valent P. Willmann M, et al. Among authors: witzeneder n. Leukemia. 2023 May;37(5):1162-1165. doi: 10.1038/s41375-023-01871-7. Epub 2023 Mar 14. Leukemia. 2023. PMID: 36918646 Free PMC article. No abstract available.
CDK4/CDK6 Inhibitors Synergize with Midostaurin, Avapritinib, and Nintedanib in Inducing Growth Inhibition in KIT D816V+ Neoplastic Mast Cells.
Schneeweiss-Gleixner M, Filik Y, Stefanzl G, Berger D, Sadovnik I, Bauer K, Smiljkovic D, Eisenwort G, Witzeneder N, Greiner G, Hoermann G, Schiefer AI, Schwaab J, Jawhar M, Reiter A, Sperr WR, Arock M, Valent P, Gleixner KV. Schneeweiss-Gleixner M, et al. Among authors: witzeneder n. Cancers (Basel). 2022 Jun 23;14(13):3070. doi: 10.3390/cancers14133070. Cancers (Basel). 2022. PMID: 35804842 Free PMC article.
LMO3 reprograms visceral adipocyte metabolism during obesity.
Wagner G, Fenzl A, Lindroos-Christensen J, Einwallner E, Husa J, Witzeneder N, Rauscher S, Gröger M, Derdak S, Mohr T, Sutterlüty H, Klinglmüller F, Wolkerstorfer S, Fondi M, Hoermann G, Cao L, Wagner O, Kiefer FW, Esterbauer H, Bilban M. Wagner G, et al. Among authors: witzeneder n. J Mol Med (Berl). 2021 Aug;99(8):1151-1171. doi: 10.1007/s00109-021-02089-9. Epub 2021 May 20. J Mol Med (Berl). 2021. PMID: 34018016 Free PMC article.
The energy sensor AMPK orchestrates metabolic and translational adaptation in expanding T helper cells.
Mayer KA, Smole U, Zhu C, Derdak S, Minervina AA, Salnikova M, Witzeneder N, Christamentl A, Boucheron N, Waidhofer-Söllner P, Trauner M, Hoermann G, Schmetterer KG, Mamedov IZ, Bilban M, Ellmeier W, Pickl WF, Gualdoni GA, Zlabinger GJ. Mayer KA, et al. Among authors: witzeneder n. FASEB J. 2021 Apr;35(4):e21217. doi: 10.1096/fj.202001763RR. FASEB J. 2021. PMID: 33715236 Free PMC article.
Hereditary α tryptasemia is a valid genetic biomarker for severe mediator-related symptoms in mastocytosis.
Greiner G, Sprinzl B, Górska A, Ratzinger F, Gurbisz M, Witzeneder N, Schmetterer KG, Gisslinger B, Uyanik G, Hadzijusufovic E, Esterbauer H, Gleixner KV, Krauth MT, Pfeilstöcker M, Keil F, Gisslinger H, Nedoszytko B, Niedoszytko M, Sperr WR, Valent P, Hoermann G. Greiner G, et al. Among authors: witzeneder n. Blood. 2021 Jan 14;137(2):238-247. doi: 10.1182/blood.2020006157. Blood. 2021. PMID: 32777817 Free PMC article.
Microarray-Based Detection of Allergen-Reactive IgE in Patients with Mastocytosis.
Smiljkovic D, Kiss R, Lupinek C, Hoermann G, Greiner G, Witzeneder N, Krajnik G, Trautinger F, Vrtala S, Mittermann I, Kundi M, Jilma B, Valenta R, Sperr WR, Valent P. Smiljkovic D, et al. Among authors: witzeneder n. J Allergy Clin Immunol Pract. 2020 Sep;8(8):2761-2768.e16. doi: 10.1016/j.jaip.2020.04.030. Epub 2020 Apr 26. J Allergy Clin Immunol Pract. 2020. PMID: 32348913 Free PMC article.
STAT5 is Expressed in CD34+/CD38- Stem Cells and Serves as a Potential Molecular Target in Ph-Negative Myeloproliferative Neoplasms.
Hadzijusufovic E, Keller A, Berger D, Greiner G, Wingelhofer B, Witzeneder N, Ivanov D, Pecnard E, Nivarthi H, Schur FKM, Filik Y, Kornauth C, Neubauer HA, Müllauer L, Tin G, Park J, de Araujo ED, Gunning PT, Hoermann G, Gouilleux F, Kralovics R, Moriggl R, Valent P. Hadzijusufovic E, et al. Among authors: witzeneder n. Cancers (Basel). 2020 Apr 21;12(4):1021. doi: 10.3390/cancers12041021. Cancers (Basel). 2020. PMID: 32326377 Free PMC article.
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