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The copper chaperone CCS facilitates copper binding to MEK1/2 to promote kinase activation.
Grasso M, Bond GJ, Kim YJ, Boyd S, Matson Dzebo M, Valenzuela S, Tsang T, Schibrowsky NA, Alwan KB, Blackburn NJ, Burslem GM, Wittung-Stafshede P, Winkler DD, Marmorstein R, Brady DC. Grasso M, et al. J Biol Chem. 2021 Dec;297(6):101314. doi: 10.1016/j.jbc.2021.101314. Epub 2021 Oct 27. J Biol Chem. 2021. PMID: 34715128 Free PMC article.
Cisplatin binds human copper chaperone Atox1 and promotes unfolding in vitro.
Palm ME, Weise CF, Lundin C, Wingsle G, Nygren Y, Björn E, Naredi P, Wolf-Watz M, Wittung-Stafshede P. Palm ME, et al. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6951-6. doi: 10.1073/pnas.1012899108. Epub 2011 Apr 11. Proc Natl Acad Sci U S A. 2011. PMID: 21482801 Free PMC article.
Fucosylated Molecules Competitively Interfere with Cholera Toxin Binding to Host Cells.
Wands AM, Cervin J, Huang H, Zhang Y, Youn G, Brautigam CA, Matson Dzebo M, Björklund P, Wallenius V, Bright DK, Bennett CS, Wittung-Stafshede P, Sampson NS, Yrlid U, Kohler JJ. Wands AM, et al. ACS Infect Dis. 2018 May 11;4(5):758-770. doi: 10.1021/acsinfecdis.7b00085. Epub 2018 Feb 22. ACS Infect Dis. 2018. PMID: 29411974 Free PMC article.
222 results