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Targeting long non-coding RNA NUDT6 enhances smooth muscle cell survival and limits vascular disease progression.
Winter H, Winski G, Busch A, Chernogubova E, Fasolo F, Wu Z, Bäcklund A, Khomtchouk BB, Van Booven DJ, Sachs N, Eckstein HH, Wittig I, Boon RA, Jin H, Maegdefessel L. Winter H, et al. Among authors: wittig i. Mol Ther. 2023 Jun 7;31(6):1775-1790. doi: 10.1016/j.ymthe.2023.04.020. Epub 2023 May 5. Mol Ther. 2023. PMID: 37147804 Free PMC article.
Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function.
Leisegang MS, Fork C, Josipovic I, Richter FM, Preussner J, Hu J, Miller MJ, Epah J, Hofmann P, Günther S, Moll F, Valasarajan C, Heidler J, Ponomareva Y, Freiman TM, Maegdefessel L, Plate KH, Mittelbronn M, Uchida S, Künne C, Stellos K, Schermuly RT, Weissmann N, Devraj K, Wittig I, Boon RA, Dimmeler S, Pullamsetti SS, Looso M, Miller FJ Jr, Brandes RP. Leisegang MS, et al. Among authors: wittig i. Circulation. 2017 Jul 4;136(1):65-79. doi: 10.1161/CIRCULATIONAHA.116.026991. Epub 2017 Mar 28. Circulation. 2017. PMID: 28351900 Free PMC article.
Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction.
Trembinski DJ, Bink DI, Theodorou K, Sommer J, Fischer A, van Bergen A, Kuo CC, Costa IG, Schürmann C, Leisegang MS, Brandes RP, Alekseeva T, Brill B, Wietelmann A, Johnson CN, Spring-Connell A, Kaulich M, Werfel S, Engelhardt S, Hirt MN, Yorgan K, Eschenhagen T, Kirchhof L, Hofmann P, Jaé N, Wittig I, Hamdani N, Bischof C, Krishnan J, Houtkooper RH, Dimmeler S, Boon RA. Trembinski DJ, et al. Among authors: wittig i. Nat Commun. 2020 Apr 27;11(1):2039. doi: 10.1038/s41467-020-15995-2. Nat Commun. 2020. PMID: 32341350 Free PMC article.
Long non-coding RNA LASSIE regulates shear stress sensing and endothelial barrier function.
Stanicek L, Lozano-Vidal N, Bink DI, Hooglugt A, Yao W, Wittig I, van Rijssel J, van Buul JD, van Bergen A, Klems A, Ramms AS, Le Noble F, Hofmann P, Szulcek R, Wang S, Offermanns S, Ercanoglu MS, Kwon HB, Stainier D, Huveneers S, Kurian L, Dimmeler S, Boon RA. Stanicek L, et al. Among authors: wittig i. Commun Biol. 2020 May 26;3(1):265. doi: 10.1038/s42003-020-0987-0. Commun Biol. 2020. PMID: 32457386 Free PMC article.
The splicing-regulatory lncRNA NTRAS sustains vascular integrity.
Fouani Y, Kirchhof L, Stanicek L, Luxán G, Heumüller AW, Knau A, Fischer A, Devraj K, John D, Neumann P, Bindereif A, Boon RA, Liebner S, Wittig I, Mogler C, Karimova M, Dimmeler S, Jaé N. Fouani Y, et al. Among authors: wittig i. EMBO Rep. 2022 Jun 7;23(6):e54157. doi: 10.15252/embr.202154157. Epub 2022 May 8. EMBO Rep. 2022. PMID: 35527520 Free PMC article.
Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2.
Oo JA, Pálfi K, Warwick T, Wittig I, Prieto-Garcia C, Matkovic V, Tomašković I, Boos F, Izquierdo Ponce J, Teichmann T, Petriukov K, Haydar S, Maegdefessel L, Wu Z, Pham MD, Krishnan J, Baker AH, Günther S, Ulrich HD, Dikic I, Leisegang MS, Brandes RP. Oo JA, et al. Among authors: wittig i. Cell Rep. 2022 Nov 15;41(7):111670. doi: 10.1016/j.celrep.2022.111670. Cell Rep. 2022. PMID: 36384122 Free PMC article.
The endothelial-enriched lncRNA LINC00607 mediates angiogenic function.
Boos F, Oo JA, Warwick T, Günther S, Izquierdo Ponce J, Lopez M, Rafii D, Buchmann G, Pham MD, Msheik ZS, Li T, Seredinski S, Haydar S, Kashefiolasl S, Plate KH, Behr R, Mietsch M, Krishnan J, Pullamsetti SS, Bibli SI, Hinkel R, Baker AH, Boon RA, Schulz MH, Wittig I, Miller FJ Jr, Brandes RP, Leisegang MS. Boos F, et al. Among authors: wittig i. Basic Res Cardiol. 2023 Jan 26;118(1):5. doi: 10.1007/s00395-023-00978-3. Basic Res Cardiol. 2023. PMID: 36700983 Free PMC article.
204 results