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S-glutathiolation impairs phosphoregulation and function of cardiac myosin-binding protein C in human heart failure.
Stathopoulou K, Wittig I, Heidler J, Piasecki A, Richter F, Diering S, van der Velden J, Buck F, Donzelli S, Schröder E, Wijnker PJ, Voigt N, Dobrev D, Sadayappan S, Eschenhagen T, Carrier L, Eaton P, Cuello F. Stathopoulou K, et al. Among authors: wittig i. FASEB J. 2016 May;30(5):1849-64. doi: 10.1096/fj.201500048. Epub 2016 Feb 2. FASEB J. 2016. PMID: 26839380 Free PMC article.
These oxidation events abrogate protein kinase-mediated phosphorylation of cMyBP-C and therefore potentially contribute to the reduction of its phosphorylation and the contractile dysfunction observed in human heart failure.-Stathopoulou, K., Wittig, I., Heidler, J. …
These oxidation events abrogate protein kinase-mediated phosphorylation of cMyBP-C and therefore potentially contribute to the reduction of …
Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue.
Rhoden A, Friedrich FW, Brandt T, Raabe J, Schweizer M, Meisterknecht J, Wittig I, Ulmer BM, Klampe B, Uebeler J, Piasecki A, Lorenz K, Eschenhagen T, Hansen A, Cuello F. Rhoden A, et al. Among authors: wittig i. Redox Biol. 2021 May;41:101951. doi: 10.1016/j.redox.2021.101951. Epub 2021 Mar 31. Redox Biol. 2021. PMID: 33831709 Free PMC article.
Generator-specific targets of mitochondrial reactive oxygen species.
Bleier L, Wittig I, Heide H, Steger M, Brandt U, Dröse S. Bleier L, et al. Among authors: wittig i. Free Radic Biol Med. 2015 Jan;78:1-10. doi: 10.1016/j.freeradbiomed.2014.10.511. Epub 2014 Oct 29. Free Radic Biol Med. 2015. PMID: 25451644
Genetic deletion of Nox4 enhances cancerogen-induced formation of solid tumors.
Helfinger V, Freiherr von Gall F, Henke N, Kunze MM, Schmid T, Rezende F, Heidler J, Wittig I, Radeke HH, Marschall V, Anderson K, Shah AM, Fulda S, Brüne B, Brandes RP, Schröder K. Helfinger V, et al. Among authors: wittig i. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2020152118. doi: 10.1073/pnas.2020152118. Proc Natl Acad Sci U S A. 2021. PMID: 33836590 Free PMC article.
204 results