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Page 1
A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment.
Scholz S, Sela E, Blaha L, Braunbeck T, Galay-Burgos M, García-Franco M, Guinea J, Klüver N, Schirmer K, Tanneberger K, Tobor-Kapłon M, Witters H, Belanger S, Benfenati E, Creton S, Cronin MT, Eggen RI, Embry M, Ekman D, Gourmelon A, Halder M, Hardy B, Hartung T, Hubesch B, Jungmann D, Lampi MA, Lee L, Léonard M, Küster E, Lillicrap A, Luckenbach T, Murk AJ, Navas JM, Peijnenburg W, Repetto G, Salinas E, Schüürmann G, Spielmann H, Tollefsen KE, Walter-Rohde S, Whale G, Wheeler JR, Winter MJ. Scholz S, et al. Among authors: witters h. Regul Toxicol Pharmacol. 2013 Dec;67(3):506-30. doi: 10.1016/j.yrtph.2013.10.003. Epub 2013 Oct 23. Regul Toxicol Pharmacol. 2013. PMID: 24161465 Review.
OECD validation study to assess intra- and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing.
Busquet F, Strecker R, Rawlings JM, Belanger SE, Braunbeck T, Carr GJ, Cenijn P, Fochtman P, Gourmelon A, Hübler N, Kleensang A, Knöbel M, Kussatz C, Legler J, Lillicrap A, Martínez-Jerónimo F, Polleichtner C, Rzodeczko H, Salinas E, Schneider KE, Scholz S, van den Brandhof EJ, van der Ven LT, Walter-Rohde S, Weigt S, Witters H, Halder M. Busquet F, et al. Among authors: witters h. Regul Toxicol Pharmacol. 2014 Aug;69(3):496-511. doi: 10.1016/j.yrtph.2014.05.018. Epub 2014 May 27. Regul Toxicol Pharmacol. 2014. PMID: 24874798 Free article.
Cell-based data to predict the toxicity of chemicals to fish. Commentary on the manuscript by Rodrigues et al., 2019. Cell-based assays seem not to accurately predict fish short-term toxicity of pesticides. Environmental Pollution 252:476-482.
Schirmer K, Stadnicka-Michalak J, Belanger SE, Blaha L, Bols NC, Dyer SD, Embry MR, Fischer M, Halder M, Hermens J, Hultman MT, Kramer N, Laue H, Lee LE, Lillicrap A, Natsch A, Segner H, Tanneberger K, Tollefsen KE, Werner I, Witters H, Zupanic A. Schirmer K, et al. Among authors: witters h. Environ Pollut. 2019 Nov;254(Pt B):113060. doi: 10.1016/j.envpol.2019.113060. Environ Pollut. 2019. PMID: 31540601 No abstract available.
Zebrafish embryos as an alternative to animal experiments--a commentary on the definition of the onset of protected life stages in animal welfare regulations.
Strähle U, Scholz S, Geisler R, Greiner P, Hollert H, Rastegar S, Schumacher A, Selderslaghs I, Weiss C, Witters H, Braunbeck T. Strähle U, et al. Among authors: witters h. Reprod Toxicol. 2012 Apr;33(2):128-32. doi: 10.1016/j.reprotox.2011.06.121. Epub 2011 Jun 25. Reprod Toxicol. 2012. PMID: 21726626 Review.
Repeatability and Reproducibility of the RTgill-W1 Cell Line Assay for Predicting Fish Acute Toxicity.
Fischer M, Belanger SE, Berckmans P, Bernhard MJ, Bláha L, Coman Schmid DE, Dyer SD, Haupt T, Hermens JLM, Hultman MT, Laue H, Lillicrap A, Mlnaříková M, Natsch A, Novák J, Sinnige TL, Tollefsen KE, von Niederhäusern V, Witters H, Županič A, Schirmer K. Fischer M, et al. Among authors: witters h. Toxicol Sci. 2019 Jun 1;169(2):353-364. doi: 10.1093/toxsci/kfz057. Toxicol Sci. 2019. PMID: 30825313 Free PMC article.
Expert opinion on toxicity profiling--report from a NORMAN expert group meeting.
Hamers T, Legler J, Blaha L, Hylland K, Marigomez I, Schipper CA, Segner H, Vethaak AD, Witters H, de Zwart D, Leonards PE. Hamers T, et al. Among authors: witters h. Integr Environ Assess Manag. 2013 Apr;9(2):185-91. doi: 10.1002/ieam.1395. Epub 2013 Feb 19. Integr Environ Assess Manag. 2013. PMID: 23307398
Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes.
Fritsche E, Grandjean P, Crofton KM, Aschner M, Goldberg A, Heinonen T, Hessel EVS, Hogberg HT, Bennekou SH, Lein PJ, Leist M, Mundy WR, Paparella M, Piersma AH, Sachana M, Schmuck G, Solecki R, Terron A, Monnet-Tschudi F, Wilks MF, Witters H, Zurich MG, Bal-Price A. Fritsche E, et al. Among authors: witters h. Toxicol Appl Pharmacol. 2018 Sep 1;354:3-6. doi: 10.1016/j.taap.2018.02.004. Epub 2018 Feb 12. Toxicol Appl Pharmacol. 2018. PMID: 29447839 Free PMC article.
A Systematic Review to Compare Chemical Hazard Predictions of the Zebrafish Embryotoxicity Test With Mammalian Prenatal Developmental Toxicity.
Hoffmann S, Marigliani B, Akgün-Ölmez SG, Ireland D, Cruz R, Busquet F, Flick B, Lalu M, Ghandakly EC, de Vries RBM, Witters H, Wright RA, Ölmez M, Willett C, Hartung T, Stephens ML, Tsaioun K. Hoffmann S, et al. Among authors: witters h. Toxicol Sci. 2021 Aug 30;183(1):14-35. doi: 10.1093/toxsci/kfab072. Toxicol Sci. 2021. PMID: 34109416 Free PMC article.
64 results