Witten J - Search Results

1

Enhancing the immunogenicity of lipid-nanoparticle mRNA vaccines by adjuvanting the ionizable lipid and the mRNA.

Li B, Jiang AY, Raji I, Atyeo C, Raimondo TM, Gordon AGR, Rhym LH, Samad T, MacIsaac C, Witten J, Mughal H, Chicz TM, Xu Y, McNamara RP, Bhatia S, Alter G, Langer R, Anderson DG. Li B, et al. Among authors: witten j. Nat Biomed Eng. 2023 Sep 7. doi: 10.1038/s41551-023-01082-6. Online ahead of print. Nat Biomed Eng. 2023. PMID: 37679571

2

Selective permeability of mucus barriers.

Witten J, Samad T, Ribbeck K. Witten J, et al. Curr Opin Biotechnol. 2018 Aug;52:124-133. doi: 10.1016/j.copbio.2018.03.010. Epub 2018 Apr 16. Curr Opin Biotechnol. 2018. PMID: 29674157 Free PMC article. Review.

3

Molecular Characterization of Mucus Binding.

Witten J, Samad T, Ribbeck K. Witten J, et al. Biomacromolecules. 2019 Apr 8;20(4):1505-1513. doi: 10.1021/acs.biomac.8b01467. Epub 2019 Mar 12. Biomacromolecules. 2019. PMID: 30779551 Free PMC article.

4

Mucus and Mucin Environments Reduce the Efficacy of Polymyxin and Fluoroquinolone Antibiotics against Pseudomonas aeruginosa.

Samad T, Co JY, Witten J, Ribbeck K. Samad T, et al. Among authors: witten j. ACS Biomater Sci Eng. 2019 Mar 11;5(3):1189-1194. doi: 10.1021/acsbiomaterials.8b01054. Epub 2019 Feb 22. ACS Biomater Sci Eng. 2019. PMID: 33405639 Free PMC article.

5

Spatial configuration of charge and hydrophobicity tune particle transport through mucus.

Samad T, Witten J, Grodzinsky AJ, Ribbeck K. Samad T, et al. Among authors: witten j. Biophys J. 2022 Jan 18;121(2):277-287. doi: 10.1016/j.bpj.2021.12.018. Epub 2021 Dec 21. Biophys J. 2022. PMID: 34951982 Free PMC article.

6

Combinatorial development of nebulized mRNA delivery formulations for the lungs.

Jiang AY, Witten J, Raji IO, Eweje F, MacIsaac C, Meng S, Oladimeji FA, Hu Y, Manan RS, Langer R, Anderson DG. Jiang AY, et al. Among authors: witten j. Nat Nanotechnol. 2024 Mar;19(3):364-375. doi: 10.1038/s41565-023-01548-3. Epub 2023 Nov 20. Nat Nanotechnol. 2024. PMID: 37985700 Free PMC article.

7

The particle in the spider's web: transport through biological hydrogels.

Witten J, Ribbeck K. Witten J, et al. Nanoscale. 2017 Jun 22;9(24):8080-8095. doi: 10.1039/c6nr09736g. Nanoscale. 2017. PMID: 28580973 Free PMC article. Review.

8

Comparison of Physicochemical Properties of Native Mucus and Reconstituted Mucin Gels.

Wagner CE, Krupkin M, Smith-Dupont KB, Wu CM, Bustos NA, Witten J, Ribbeck K. Wagner CE, et al. Among authors: witten j. Biomacromolecules. 2023 Feb 13;24(2):628-639. doi: 10.1021/acs.biomac.2c01016. Epub 2023 Feb 2. Biomacromolecules. 2023. PMID: 36727870

9

Probing the potential of mucus permeability to signify preterm birth risk.

Smith-Dupont KB, Wagner CE, Witten J, Conroy K, Rudoltz H, Pagidas K, Snegovskikh V, House M, Ribbeck K. Smith-Dupont KB, et al. Among authors: witten j. Sci Rep. 2017 Sep 4;7(1):10302. doi: 10.1038/s41598-017-08057-z. Sci Rep. 2017. PMID: 28871085 Free PMC article.

10

Computational Insights into Avidity of Polymeric Multivalent Binders.

Zumbro E, Witten J, Alexander-Katz A. Zumbro E, et al. Among authors: witten j. Biophys J. 2019 Sep 3;117(5):892-902. doi: 10.1016/j.bpj.2019.07.026. Epub 2019 Jul 24. Biophys J. 2019. PMID: 31400918 Free PMC article.

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