Witte L - Search Results

1

Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.

Butler JM, Nolan DJ, Vertes EL, Varnum-Finney B, Kobayashi H, Hooper AT, Seandel M, Shido K, White IA, Kobayashi M, Witte L, May C, Shawber C, Kimura Y, Kitajewski J, Rosenwaks Z, Bernstein ID, Rafii S. Butler JM, et al. Among authors: witte l. Cell Stem Cell. 2010 Mar 5;6(3):251-64. doi: 10.1016/j.stem.2010.02.001. Cell Stem Cell. 2010. PMID: 20207228 Free PMC article.

2

Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells.

Hooper AT, Butler JM, Nolan DJ, Kranz A, Iida K, Kobayashi M, Kopp HG, Shido K, Petit I, Yanger K, James D, Witte L, Zhu Z, Wu Y, Pytowski B, Rosenwaks Z, Mittal V, Sato TN, Rafii S. Hooper AT, et al. Among authors: witte l. Cell Stem Cell. 2009 Mar 6;4(3):263-74. doi: 10.1016/j.stem.2009.01.006. Cell Stem Cell. 2009. PMID: 19265665 Free PMC article.

3

Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells.

Hattori K, Dias S, Heissig B, Hackett NR, Lyden D, Tateno M, Hicklin DJ, Zhu Z, Witte L, Crystal RG, Moore MA, Rafii S. Hattori K, et al. Among authors: witte l. J Exp Med. 2001 May 7;193(9):1005-14. doi: 10.1084/jem.193.9.1005. J Exp Med. 2001. PMID: 11342585 Free PMC article.

4

Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis.

Avecilla ST, Hattori K, Heissig B, Tejada R, Liao F, Shido K, Jin DK, Dias S, Zhang F, Hartman TE, Hackett NR, Crystal RG, Witte L, Hicklin DJ, Bohlen P, Eaton D, Lyden D, de Sauvage F, Rafii S. Avecilla ST, et al. Among authors: witte l. Nat Med. 2004 Jan;10(1):64-71. doi: 10.1038/nm973. Epub 2003 Dec 21. Nat Med. 2004. PMID: 14702636

5

Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment.

Hattori K, Heissig B, Wu Y, Dias S, Tejada R, Ferris B, Hicklin DJ, Zhu Z, Bohlen P, Witte L, Hendrikx J, Hackett NR, Crystal RG, Moore MA, Werb Z, Lyden D, Rafii S. Hattori K, et al. Among authors: witte l. Nat Med. 2002 Aug;8(8):841-9. doi: 10.1038/nm740. Epub 2002 Jul 1. Nat Med. 2002. PMID: 12091880 Free PMC article.

6

The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma.

Wu Y, Hooper AT, Zhong Z, Witte L, Bohlen P, Rafii S, Hicklin DJ. Wu Y, et al. Among authors: witte l. Int J Cancer. 2006 Oct 1;119(7):1519-29. doi: 10.1002/ijc.21865. Int J Cancer. 2006. PMID: 16671089 Free article.

7

Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias.

Dias S, Hattori K, Heissig B, Zhu Z, Wu Y, Witte L, Hicklin DJ, Tateno M, Bohlen P, Moore MA, Rafii S. Dias S, et al. Among authors: witte l. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10857-62. doi: 10.1073/pnas.191117498. Proc Natl Acad Sci U S A. 2001. PMID: 11553814 Free PMC article.

8

Vascular trauma induces rapid but transient mobilization of VEGFR2(+)AC133(+) endothelial precursor cells.

Gill M, Dias S, Hattori K, Rivera ML, Hicklin D, Witte L, Girardi L, Yurt R, Himel H, Rafii S. Gill M, et al. Among authors: witte l. Circ Res. 2001 Feb 2;88(2):167-74. doi: 10.1161/01.res.88.2.167. Circ Res. 2001. PMID: 11157668 Clinical Trial.

9

Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors.

Peichev M, Naiyer AJ, Pereira D, Zhu Z, Lane WJ, Williams M, Oz MC, Hicklin DJ, Witte L, Moore MA, Rafii S. Peichev M, et al. Among authors: witte l. Blood. 2000 Feb 1;95(3):952-8. Blood. 2000. PMID: 10648408 Free article.

10

The effects of Flk-2/flt3 ligand as compared with c-kit ligand on short-term and long-term proliferation of CD34+ hematopoietic progenitors elicited from human fetal liver, umbilical cord blood, bone marrow, and mobilized peripheral blood.

Shapiro F, Pytowski B, Rafii S, Witte L, Hicklin DJ, Yao TJ, Moore MA. Shapiro F, et al. Among authors: witte l. J Hematother. 1996 Dec;5(6):655-62. doi: 10.1089/scd.1.1996.5.655. J Hematother. 1996. PMID: 9117254

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