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CTLA4 protects against maladaptive cytotoxicity during the differentiation of effector and follicular CD4+ T cells.
Hao Y, Miraghazadeh B, Chand R, Davies AR, Cardinez C, Kwong K, Downes MB, Sweet RA, Cañete PF, D'Orsogna LJ, Fulcher DA, Choo S, Yip D, Peters G, Yip S, Witney MJ, Nekrasov M, Feng ZP, Tscharke DC, Vinuesa CG, Cook MC. Hao Y, et al. Among authors: witney mj. Cell Mol Immunol. 2023 Jul;20(7):777-793. doi: 10.1038/s41423-023-01027-8. Epub 2023 May 9. Cell Mol Immunol. 2023. PMID: 37161048 Free PMC article.
Most viral peptides displayed by class I MHC on infected cells are immunogenic.
Croft NP, Smith SA, Pickering J, Sidney J, Peters B, Faridi P, Witney MJ, Sebastian P, Flesch IEA, Heading SL, Sette A, La Gruta NL, Purcell AW, Tscharke DC. Croft NP, et al. Among authors: witney mj. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3112-3117. doi: 10.1073/pnas.1815239116. Epub 2019 Feb 4. Proc Natl Acad Sci U S A. 2019. PMID: 30718433 Free PMC article.