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Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression.
Opzoomer JW, Anstee JE, Dean I, Hill EJ, Bouybayoune I, Caron J, Muliaditan T, Gordon P, Sosnowska D, Nuamah R, Pinder SE, Ng T, Dazzi F, Kordasti S, Withers DR, Lawrence T, Arnold JN. Opzoomer JW, et al. Among authors: withers dr. Sci Adv. 2021 Nov 5;7(45):eabg9518. doi: 10.1126/sciadv.abg9518. Epub 2021 Nov 3. Sci Adv. 2021. PMID: 34730997 Free PMC article.
RORγt+ Innate Lymphoid Cells Promote Lymph Node Metastasis of Breast Cancers.
Irshad S, Flores-Borja F, Lawler K, Monypenny J, Evans R, Male V, Gordon P, Cheung A, Gazinska P, Noor F, Wong F, Grigoriadis A, Fruhwirth GO, Barber PR, Woodman N, Patel D, Rodriguez-Justo M, Owen J, Martin SG, Pinder SE, Gillett CE, Poland SP, Ameer-Beg S, McCaughan F, Carlin LM, Hasan U, Withers DR, Lane P, Vojnovic B, Quezada SA, Ellis P, Tutt AN, Ng T. Irshad S, et al. Among authors: withers dr. Cancer Res. 2017 Mar 1;77(5):1083-1096. doi: 10.1158/0008-5472.CAN-16-0598. Epub 2017 Jan 12. Cancer Res. 2017. PMID: 28082403 Free article.
In vivo labeling reveals continuous trafficking of TCF-1+ T cells between tumor and lymphoid tissue.
Li Z, Tuong ZK, Dean I, Willis C, Gaspal F, Fiancette R, Idris S, Kennedy B, Ferdinand JR, Peñalver A, Cabantous M, Murtuza Baker S, Fry JW, Carlesso G, Hammond SA, Dovedi SJ, Hepworth MR, Clatworthy MR, Withers DR. Li Z, et al. Among authors: withers dr. J Exp Med. 2022 Jun 6;219(6):e20210749. doi: 10.1084/jem.20210749. Epub 2022 Apr 26. J Exp Med. 2022. PMID: 35472220 Free PMC article.
Tumour-retained activated CCR7+ dendritic cells are heterogeneous and regulate local anti-tumour cytolytic activity.
Lee CYC, Kennedy BC, Richoz N, Dean I, Tuong ZK, Gaspal F, Li Z, Willis C, Hasegawa T, Whiteside SK, Posner DA, Carlesso G, Hammond SA, Dovedi SJ, Roychoudhuri R, Withers DR, Clatworthy MR. Lee CYC, et al. Among authors: withers dr. Nat Commun. 2024 Jan 24;15(1):682. doi: 10.1038/s41467-024-44787-1. Nat Commun. 2024. PMID: 38267413 Free PMC article.
Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity.
Dean I, Lee CYC, Tuong ZK, Li Z, Tibbitt CA, Willis C, Gaspal F, Kennedy BC, Matei-Rascu V, Fiancette R, Nordenvall C, Lindforss U, Baker SM, Stockmann C, Sexl V, Hammond SA, Dovedi SJ, Mjösberg J, Hepworth MR, Carlesso G, Clatworthy MR, Withers DR. Dean I, et al. Among authors: withers dr. Nat Commun. 2024 Jan 24;15(1):683. doi: 10.1038/s41467-024-44789-z. Nat Commun. 2024. PMID: 38267402 Free PMC article.
A Stromal Cell Niche for Human and Mouse Type 3 Innate Lymphoid Cells.
Hoorweg K, Narang P, Li Z, Thuery A, Papazian N, Withers DR, Coles MC, Cupedo T. Hoorweg K, et al. Among authors: withers dr. J Immunol. 2015 Nov 1;195(9):4257-4263. doi: 10.4049/jimmunol.1402584. Epub 2015 Sep 16. J Immunol. 2015. PMID: 26378073 Free PMC article.
CLEC-2 is required for development and maintenance of lymph nodes.
Bénézech C, Nayar S, Finney BA, Withers DR, Lowe K, Desanti GE, Marriott CL, Watson SP, Caamaño JH, Buckley CD, Barone F. Bénézech C, et al. Among authors: withers dr. Blood. 2014 May 15;123(20):3200-7. doi: 10.1182/blood-2013-03-489286. Epub 2014 Feb 14. Blood. 2014. PMID: 24532804 Free PMC article.
99 results