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Pharmacological characterization of FE 202158, a novel, potent, selective, and short-acting peptidic vasopressin V1a receptor full agonist for the treatment of vasodilatory hypotension.
Laporte R, Kohan A, Heitzmann J, Wisniewska H, Toy J, La E, Tariga H, Alagarsamy S, Ly B, Dykert J, Qi S, Wisniewski K, Galyean R, Croston G, Schteingart CD, Rivière PJ. Laporte R, et al. Among authors: wisniewski k. J Pharmacol Exp Ther. 2011 Jun;337(3):786-96. doi: 10.1124/jpet.111.178848. Epub 2011 Mar 16. J Pharmacol Exp Ther. 2011. PMID: 21411496
New, potent, selective, and short-acting peptidic V1a receptor agonists.
Wisniewski K, Galyean R, Tariga H, Alagarsamy S, Croston G, Heitzmann J, Kohan A, Wisniewska H, Laporte R, Rivière PJ, Schteingart CD. Wisniewski K, et al. J Med Chem. 2011 Jul 14;54(13):4388-98. doi: 10.1021/jm200278m. Epub 2011 Jun 20. J Med Chem. 2011. PMID: 21688787
New, potent, and selective peptidic oxytocin receptor agonists.
Wiśniewski K, Alagarsamy S, Galyean R, Tariga H, Thompson D, Ly B, Wiśniewska H, Qi S, Croston G, Laporte R, Rivière PJ, Schteingart CD. Wiśniewski K, et al. J Med Chem. 2014 Jun 26;57(12):5306-17. doi: 10.1021/jm500365s. Epub 2014 Jun 12. J Med Chem. 2014. PMID: 24874785
The selective vasopressin type 1a receptor agonist selepressin (FE 202158) blocks vascular leak in ovine severe sepsis*.
Maybauer MO, Maybauer DM, Enkhbaatar P, Laporte R, Wiśniewska H, Traber LD, Lin C, Fan J, Hawkins HK, Cox RA, Wiśniewski K, Schteingart CD, Landry DW, Rivière PJ, Traber DL. Maybauer MO, et al. Among authors: wisniewski k. Crit Care Med. 2014 Jul;42(7):e525-e533. doi: 10.1097/CCM.0000000000000300. Crit Care Med. 2014. PMID: 24674922 Free PMC article.
Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral kappa-opioid receptors.
Vanderah TW, Largent-Milnes T, Lai J, Porreca F, Houghten RA, Menzaghi F, Wisniewski K, Stalewski J, Sueiras-Diaz J, Galyean R, Schteingart C, Junien JL, Trojnar J, Rivière PJ. Vanderah TW, et al. Among authors: wisniewski k. Eur J Pharmacol. 2008 Mar 31;583(1):62-72. doi: 10.1016/j.ejphar.2008.01.011. Epub 2008 Jan 24. Eur J Pharmacol. 2008. PMID: 18282565
495 results