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F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd.
Morris J, Wishka DG, Lopez OD, Rudchenko V, Huang G, Hoffman SN, Borgel S, Georgius K, Carter J, Stotler H, Kunkel MW, Collins JM, Hollingshead MG, Teicher BA. Morris J, et al. Among authors: wishka dg. Mol Cancer Ther. 2021 Apr;20(4):625-631. doi: 10.1158/1535-7163.MCT-20-0738. Mol Cancer Ther. 2021. PMID: 33811149 Free PMC article.
The development of β-selective glycosylation reactions with benzyl substituted 2-deoxy-1,4-dithio-D-erythro-pentofuranosides: enabling practical multi-gram syntheses of 4'-Thio-2'-deoxycytidine (T-dCyd) and 5-aza-4'-thio-2'-deoxycytidine (aza-T-dCyd) to support clinical development.
Wishka DG, Lopez OD, Rudchenko VF, Huang G, Bahde R, Kumar V, Denysenko SM, Zhang L, Zhang M, Teicher BA, Morris J. Wishka DG, et al. Nucleosides Nucleotides Nucleic Acids. 2021;40(1):68-95. doi: 10.1080/15257770.2020.1832694. Epub 2020 Oct 16. Nucleosides Nucleotides Nucleic Acids. 2021. PMID: 33063584
PF-03814735, an orally bioavailable small molecule aurora kinase inhibitor for cancer therapy.
Jani JP, Arcari J, Bernardo V, Bhattacharya SK, Briere D, Cohen BD, Coleman K, Christensen JG, Emerson EO, Jakowski A, Hook K, Los G, Moyer JD, Pruimboom-Brees I, Pustilnik L, Rossi AM, Steyn SJ, Su C, Tsaparikos K, Wishka D, Yoon K, Jakubczak JL. Jani JP, et al. Mol Cancer Ther. 2010 Apr;9(4):883-94. doi: 10.1158/1535-7163.MCT-09-0915. Epub 2010 Mar 30. Mol Cancer Ther. 2010. PMID: 20354118
Synthesis of lipoxin B.
Morris J, Wishka DG. Morris J, et al. Among authors: wishka dg. Adv Prostaglandin Thromboxane Leukot Res. 1986;16:99-109. Adv Prostaglandin Thromboxane Leukot Res. 1986. PMID: 2949568 Review. No abstract available.
Synthesis and biological evaluation of antiplatelet 2-aminochromones.
Morris J, Wishka DG, Lin AH, Humphrey WR, Wiltse AL, Gammill RB, Judge TM, Bisaha SN, Olds NL, Jacob CS, et al. Morris J, et al. Among authors: wishka dg. J Med Chem. 1993 Jul 9;36(14):2026-32. doi: 10.1021/jm00066a012. J Med Chem. 1993. PMID: 8336341
29 results