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Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly.
Stanton C, Sun J, Nutsch K, Rosarda JD, Nguyen T, Li-Ma C, Njomen E, Melillo B, Kutseikin S, Saez E, Cravatt BF, Teijaro JR, Wiseman RL, Bollong MJ. Stanton C, et al. Among authors: wiseman rl. ACS Chem Biol. 2024 Feb 16;19(2):254-265. doi: 10.1021/acschembio.3c00330. Epub 2024 Jan 10. ACS Chem Biol. 2024. PMID: 38198472
A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics.
Giadone RM, Rosarda JD, Akepati PR, Thomas AC, Boldbaatar B, James MF, Wilson AA, Sanchorawala V, Connors LH, Berk JL, Wiseman RL, Murphy GJ. Giadone RM, et al. Among authors: wiseman rl. Amyloid. 2018 Sep;25(3):148-155. doi: 10.1080/13506129.2018.1489228. Epub 2018 Jul 21. Amyloid. 2018. PMID: 30032658 Free PMC article.
Proteostasis and Beyond: ATF6 in Ischemic Disease.
Glembotski CC, Rosarda JD, Wiseman RL. Glembotski CC, et al. Among authors: wiseman rl. Trends Mol Med. 2019 Jun;25(6):538-550. doi: 10.1016/j.molmed.2019.03.005. Epub 2019 May 8. Trends Mol Med. 2019. PMID: 31078432 Free PMC article. Review.
Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease.
Giadone RM, Liberti DC, Matte TM, Rosarda JD, Torres-Arancivia C, Ghosh S, Diedrich JK, Pankow S, Skvir N, Jean JC, Yates JR 3rd, Wilson AA, Connors LH, Kotton DN, Wiseman RL, Murphy GJ. Giadone RM, et al. Among authors: wiseman rl. Stem Cell Reports. 2020 Aug 11;15(2):515-528. doi: 10.1016/j.stemcr.2020.07.003. Epub 2020 Jul 30. Stem Cell Reports. 2020. PMID: 32735824 Free PMC article.
125 results