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Inhibition of the PCAF histone acetyl transferase and cell proliferation by isothiazolones.
Bioorg Med Chem. 2009 Jan 15;17(2):460-6. doi: 10.1016/j.bmc.2008.12.008. Epub 2008 Dec 13.
Bioorg Med Chem. 2009.
PMID: 19111471
Isothiazolones; thiol-reactive inhibitors of cysteine protease cathepsin B and histone acetyltransferase PCAF.
Wisastra R, Ghizzoni M, Maarsingh H, Minnaard AJ, Haisma HJ, Dekker FJ.
Wisastra R, et al.
Org Biomol Chem. 2011 Mar 21;9(6):1817-22. doi: 10.1039/c0ob00464b. Epub 2011 Jan 25.
Org Biomol Chem. 2011.
PMID: 21267493
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Anacardic acid derived salicylates are inhibitors or activators of lipoxygenases.
Wisastra R, Ghizzoni M, Boltjes A, Haisma HJ, Dekker FJ.
Wisastra R, et al.
Bioorg Med Chem. 2012 Aug 15;20(16):5027-32. doi: 10.1016/j.bmc.2012.06.019. Epub 2012 Jun 21.
Bioorg Med Chem. 2012.
PMID: 22789707
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Discovery of a novel activator of 5-lipoxygenase from an anacardic acid derived compound collection.
Wisastra R, Kok PA, Eleftheriadis N, Baumgartner MP, Camacho CJ, Haisma HJ, Dekker FJ.
Wisastra R, et al.
Bioorg Med Chem. 2013 Dec 15;21(24):7763-78. doi: 10.1016/j.bmc.2013.10.015. Epub 2013 Oct 23.
Bioorg Med Chem. 2013.
PMID: 24231650
Free PMC article.
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A dual inhibitor of matrix metalloproteinases and a disintegrin and metalloproteinases, [¹⁸F]FB-ML5, as a molecular probe for non-invasive MMP/ADAM-targeted imaging.
Matusiak N, Castelli R, Tuin AW, Overkleeft HS, Wisastra R, Dekker FJ, Prély LM, Bischoff R, van Waarde A, Dierckx RA, Elsinga PH.
Matusiak N, et al. Among authors: wisastra r.
Bioorg Med Chem. 2015 Jan 1;23(1):192-202. doi: 10.1016/j.bmc.2014.11.013. Epub 2014 Nov 15.
Bioorg Med Chem. 2015.
PMID: 25438884
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Antibody-free detection of protein tyrosine nitration in tissue sections.
Wisastra R, Poelstra K, Bischoff R, Maarsingh H, Haisma HJ, Dekker FJ.
Wisastra R, et al.
Chembiochem. 2011 Sep 5;12(13):2016-20. doi: 10.1002/cbic.201100148. Epub 2011 Jul 11.
Chembiochem. 2011.
PMID: 21748837
No abstract available.
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Inflammation, Cancer and Oxidative Lipoxygenase Activity are Intimately Linked.
Wisastra R, Dekker FJ.
Wisastra R, et al.
Cancers (Basel). 2014 Jul 17;6(3):1500-21. doi: 10.3390/cancers6031500.
Cancers (Basel). 2014.
PMID: 25037020
Free PMC article.
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Enrichment and detection of tyrosine-nitrated proteins.
Dekker F, Abello N, Wisastra R, Bischoff R.
Dekker F, et al. Among authors: wisastra r.
Curr Protoc Protein Sci. 2012 Aug;Chapter 14:14.13.1-14.13.19. doi: 10.1002/0471140864.ps1413s69.
Curr Protoc Protein Sci. 2012.
PMID: 22851496
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