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Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo.
Atreya R, Mudter J, Finotto S, Müllberg J, Jostock T, Wirtz S, Schütz M, Bartsch B, Holtmann M, Becker C, Strand D, Czaja J, Schlaak JF, Lehr HA, Autschbach F, Schürmann G, Nishimoto N, Yoshizaki K, Ito H, Kishimoto T, Galle PR, Rose-John S, Neurath MF. Atreya R, et al. Among authors: wirtz s. Nat Med. 2000 May;6(5):583-8. doi: 10.1038/75068. Nat Med. 2000. PMID: 10802717
CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes.
Tiede I, Fritz G, Strand S, Poppe D, Dvorsky R, Strand D, Lehr HA, Wirtz S, Becker C, Atreya R, Mudter J, Hildner K, Bartsch B, Holtmann M, Blumberg R, Walczak H, Iven H, Galle PR, Ahmadian MR, Neurath MF. Tiede I, et al. Among authors: wirtz s. J Clin Invest. 2003 Apr;111(8):1133-45. doi: 10.1172/JCI16432. J Clin Invest. 2003. PMID: 12697733 Free PMC article.
TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.
Becker C, Fantini MC, Schramm C, Lehr HA, Wirtz S, Nikolaev A, Burg J, Strand S, Kiesslich R, Huber S, Ito H, Nishimoto N, Yoshizaki K, Kishimoto T, Galle PR, Blessing M, Rose-John S, Neurath MF. Becker C, et al. Among authors: wirtz s. Immunity. 2004 Oct;21(4):491-501. doi: 10.1016/j.immuni.2004.07.020. Immunity. 2004. PMID: 15485627 Free article.
IL-6 signaling promotes tumor growth in colorectal cancer.
Becker C, Fantini MC, Wirtz S, Nikolaev A, Lehr HA, Galle PR, Rose-John S, Neurath MF. Becker C, et al. Among authors: wirtz s. Cell Cycle. 2005 Feb;4(2):217-20. Epub 2005 Feb 3. Cell Cycle. 2005. PMID: 15655344
275 results