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Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours.
Br J Cancer. 2021 Apr;124(9):1566-1580. doi: 10.1038/s41416-021-01270-8. Epub 2021 Mar 3.
Br J Cancer. 2021.
PMID: 33658640
Free PMC article.
Correction: Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours.
Gampala S, Shah F, Zhang C, Rhodes SD, Babb O, Grimard M, Wireman RS, Rad E, Calver B, Bai RY, Staedtke V, Hulsey EL, Saadatzadeh MR, Pollok KE, Tong Y, Smith AE, Clapp DW, Tee AR, Kelley MR, Fishel ML.
Gampala S, et al. Among authors: wireman rs.
Br J Cancer. 2022 Oct;127(7):1378-1379. doi: 10.1038/s41416-022-01938-9.
Br J Cancer. 2022.
PMID: 35953714
Free PMC article.
No abstract available.
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Combined inhibition of Ref-1 and STAT3 leads to synergistic tumour inhibition in multiple cancers using 3D and in vivo tumour co-culture models.
Caston RA, Shah F, Starcher CL, Wireman R, Babb O, Grimard M, McGeown J, Armstrong L, Tong Y, Pili R, Rupert J, Zimmers TA, Elmi AN, Pollok KE, Motea EA, Kelley MR, Fishel ML.
Caston RA, et al.
J Cell Mol Med. 2021 Jan;25(2):784-800. doi: 10.1111/jcmm.16132. Epub 2020 Dec 3.
J Cell Mol Med. 2021.
PMID: 33274592
Free PMC article.
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RelA Is an Essential Target for Enhancing Cellular Responses to the DNA Repair/Ref-1 Redox Signaling Protein and Restoring Perturbated Cellular Redox Homeostasis in Mouse PDAC Cells.
Mijit M, Wireman R, Armstrong L, Gampala S, Hassan Z, Schneeweis C, Schneider G, Zhang C, Fishel ML, Kelley MR.
Mijit M, et al.
Front Oncol. 2022 Mar 24;12:826617. doi: 10.3389/fonc.2022.826617. eCollection 2022.
Front Oncol. 2022.
PMID: 35402225
Free PMC article.
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Small molecule activation of apurinic/apyrimidinic endonuclease 1 reduces DNA damage induced by cisplatin in cultured sensory neurons.
Georgiadis MM, Chen Q, Meng J, Guo C, Wireman R, Reed A, Vasko MR, Kelley MR.
Georgiadis MM, et al.
DNA Repair (Amst). 2016 May;41:32-41. doi: 10.1016/j.dnarep.2016.03.009. Epub 2016 Mar 29.
DNA Repair (Amst). 2016.
PMID: 27078577
Free PMC article.
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Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
Trilles R, Beglov D, Chen Q, He H, Wireman R, Reed A, Chennamadhavuni S, Panek JS, Brown LE, Vajda S, Porco JA Jr, Kelley MR, Georgiadis MM.
Trilles R, et al.
J Med Chem. 2019 Feb 28;62(4):1971-1988. doi: 10.1021/acs.jmedchem.8b01529. Epub 2019 Feb 6.
J Med Chem. 2019.
PMID: 30653918
Free PMC article.
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Phosphorylation site specificity of the Pak-mediated regulation of Raf-1 and cooperativity with Src.
King AJ, Wireman RS, Hamilton M, Marshall MS.
King AJ, et al. Among authors: wireman rs.
FEBS Lett. 2001 May 18;497(1):6-14. doi: 10.1016/s0014-5793(01)02425-5.
FEBS Lett. 2001.
PMID: 11376654
Free article.
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