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Towards the sustainable discovery and development of new antibiotics.
Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo PB, Glaser P, Aigle B, Bode HB, Moreira R, Li Y, Luzhetskyy A, Medema MH, Pernodet JL, Stadler M, Tormo JR, Genilloud O, Truman AW, Weissman KJ, Takano E, Sabatini S, Stegmann E, Brötz-Oesterhelt H, Wohlleben W, Seemann M, Empting M, Hirsch AKH, Loretz B, Lehr CM, Titz A, Herrmann J, Jaeger T, Alt S, Hesterkamp T, Winterhalter M, Schiefer A, Pfarr K, Hoerauf A, Graz H, Graz M, Lindvall M, Ramurthy S, Karlén A, van Dongen M, Petkovic H, Keller A, Peyrane F, Donadio S, Fraisse L, Piddock LJV, Gilbert IH, Moser HE, Müller R. Miethke M, et al. Among authors: winterhalter m. Nat Rev Chem. 2021 Oct;5(10):726-749. doi: 10.1038/s41570-021-00313-1. Epub 2021 Aug 19. Nat Rev Chem. 2021. PMID: 37118182 Review.
Towards the sustainable discovery and development of new antibiotics.
Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo PB, Glaser P, Aigle B, Bode HB, Moreira R, Li Y, Luzhetskyy A, Medema MH, Pernodet JL, Stadler M, Tormo JR, Genilloud O, Truman AW, Weissman KJ, Takano E, Sabatini S, Stegmann E, Brötz-Oesterhelt H, Wohlleben W, Seemann M, Empting M, Hirsch AKH, Loretz B, Lehr CM, Titz A, Herrmann J, Jaeger T, Alt S, Hesterkamp T, Winterhalter M, Schiefer A, Pfarr K, Hoerauf A, Graz H, Graz M, Lindvall M, Ramurthy S, Karlén A, van Dongen M, Petkovic H, Keller A, Peyrane F, Donadio S, Fraisse L, Piddock LJV, Gilbert IH, Moser HE, Müller R. Miethke M, et al. Among authors: winterhalter m. Nat Rev Chem. 2021;5(10):726-749. doi: 10.1038/s41570-021-00313-1. Epub 2021 Aug 19. Nat Rev Chem. 2021. PMID: 34426795 Free PMC article. Review.
Total synthesis and mechanism of action of the antibiotic armeniaspirol A.
Arisetti N, Fuchs HLS, Coetzee J, Orozco M, Ruppelt D, Bauer A, Heimann D, Kuhnert E, Bhamidimarri SP, Bafna JA, Hinkelmann B, Eckel K, Sieber SA, Müller PP, Herrmann J, Müller R, Winterhalter M, Steinem C, Brönstrup M. Arisetti N, et al. Among authors: winterhalter m. Chem Sci. 2021 Nov 24;12(48):16023-16034. doi: 10.1039/d1sc04290d. eCollection 2021 Dec 15. Chem Sci. 2021. PMID: 35024125 Free PMC article.
α-Amino Diphenyl Phosphonates as Novel Inhibitors of Escherichia coli ClpP Protease.
Moreno-Cinos C, Sassetti E, Salado IG, Witt G, Benramdane S, Reinhardt L, Cruz CD, Joossens J, Van der Veken P, Brötz-Oesterhelt H, Tammela P, Winterhalter M, Gribbon P, Windshügel B, Augustyns K. Moreno-Cinos C, et al. Among authors: winterhalter m. J Med Chem. 2019 Jan 24;62(2):774-797. doi: 10.1021/acs.jmedchem.8b01466. Epub 2019 Jan 11. J Med Chem. 2019. PMID: 30571121
Porins and small-molecule translocation across the outer membrane of Gram-negative bacteria.
Vergalli J, Bodrenko IV, Masi M, Moynié L, Acosta-Gutiérrez S, Naismith JH, Davin-Regli A, Ceccarelli M, van den Berg B, Winterhalter M, Pagès JM. Vergalli J, et al. Among authors: winterhalter m. Nat Rev Microbiol. 2020 Mar;18(3):164-176. doi: 10.1038/s41579-019-0294-2. Epub 2019 Dec 2. Nat Rev Microbiol. 2020. PMID: 31792365 Free article. Review.
Implication of porins in beta-lactam resistance of Providencia stuartii.
Tran QT, Mahendran KR, Hajjar E, Ceccarelli M, Davin-Regli A, Winterhalter M, Weingart H, Pagès JM. Tran QT, et al. Among authors: winterhalter m. J Biol Chem. 2010 Oct 15;285(42):32273-81. doi: 10.1074/jbc.M110.143305. Epub 2010 Jul 28. J Biol Chem. 2010. PMID: 20667831 Free PMC article.
Enrofloxacin Permeation Pathways across the Porin OmpC.
Prajapati JD, Solano CJF, Winterhalter M, Kleinekathöfer U. Prajapati JD, et al. Among authors: winterhalter m. J Phys Chem B. 2018 Feb 1;122(4):1417-1426. doi: 10.1021/acs.jpcb.7b12568. Epub 2018 Jan 22. J Phys Chem B. 2018. PMID: 29307192
294 results