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The NFKB1 promoter polymorphism (-94ins/delATTG) alters nuclear translocation of NF-κB1 in monocytes after lipopolysaccharide stimulation and is associated with increased mortality in sepsis.
Adamzik M, Schäfer S, Frey UH, Becker A, Kreuzer M, Winning S, Frede S, Steinmann J, Fandrey J, Zacharowski K, Siffert W, Peters J, Hartmann M. Adamzik M, et al. Among authors: winning s. Anesthesiology. 2013 Jan;118(1):123-33. doi: 10.1097/ALN.0b013e318277a652. Anesthesiology. 2013. PMID: 23249930 Free article.
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