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Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration.
Meka DP, Müller-Rischart AK, Nidadavolu P, Mohammadi B, Motori E, Ponna SK, Aboutalebi H, Bassal M, Annamneedi A, Finckh B, Miesbauer M, Rotermund N, Lohr C, Tatzelt J, Winklhofer KF, Kramer ER. Meka DP, et al. Among authors: winklhofer kf. J Clin Invest. 2015 May;125(5):1873-85. doi: 10.1172/JCI79300. Epub 2015 Mar 30. J Clin Invest. 2015. PMID: 25822020 Free PMC article.
Loss of parkin causes endoplasmic reticulum calcium dyshomeostasis by upregulation of reticulocalbin 1.
Rybarski M, Mrohs D, Osenberg K, Hemmersbach M, Pfeffel K, Steinkamp J, Schmidt D, Violou K, Schäning R, Schmidtke K, Bader V, Andriske M, Bohne P, Mark MD, Winklhofer KF, Lübbert H, Zhu XR. Rybarski M, et al. Among authors: winklhofer kf. Eur J Neurosci. 2023 Mar;57(5):739-761. doi: 10.1111/ejn.15917. Epub 2023 Feb 3. Eur J Neurosci. 2023. PMID: 36656174
Pathogenic mutations inactivate parkin by distinct mechanisms.
Henn IH, Gostner JM, Lackner P, Tatzelt J, Winklhofer KF. Henn IH, et al. Among authors: winklhofer kf. J Neurochem. 2005 Jan;92(1):114-22. doi: 10.1111/j.1471-4159.2004.02854.x. J Neurochem. 2005. PMID: 15606901 Free article.
105 results