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Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.
Mertens J, Paquola ACM, Ku M, Hatch E, Böhnke L, Ladjevardi S, McGrath S, Campbell B, Lee H, Herdy JR, Gonçalves JT, Toda T, Kim Y, Winkler J, Yao J, Hetzer MW, Gage FH. Mertens J, et al. Among authors: winkler j. Cell Stem Cell. 2015 Dec 3;17(6):705-718. doi: 10.1016/j.stem.2015.09.001. Epub 2015 Oct 8. Cell Stem Cell. 2015. PMID: 26456686 Free PMC article.
Acetylcholine-secreting cells improve age-induced memory deficits.
Dickinson-Anson H, Winkler J, Fisher LJ, Song HJ, Poo Mm, Gage FH. Dickinson-Anson H, et al. Among authors: winkler j. Mol Ther. 2003 Jul;8(1):51-61. doi: 10.1016/s1525-0016(03)00145-x. Mol Ther. 2003. PMID: 12842428 Free article.
Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons.
Havlicek S, Kohl Z, Mishra HK, Prots I, Eberhardt E, Denguir N, Wend H, Plötz S, Boyer L, Marchetto MC, Aigner S, Sticht H, Groemer TW, Hehr U, Lampert A, Schlötzer-Schrehardt U, Winkler J, Gage FH, Winner B. Havlicek S, et al. Among authors: winkler j. Hum Mol Genet. 2014 May 15;23(10):2527-41. doi: 10.1093/hmg/ddt644. Epub 2013 Dec 30. Hum Mol Genet. 2014. PMID: 24381312 Free PMC article.
Pattern of Functional TTX-Resistant Sodium Channels Reveals a Developmental Stage of Human iPSC- and ESC-Derived Nociceptors.
Eberhardt E, Havlicek S, Schmidt D, Link AS, Neacsu C, Kohl Z, Hampl M, Kist AM, Klinger A, Nau C, Schüttler J, Alzheimer C, Winkler J, Namer B, Winner B, Lampert A. Eberhardt E, et al. Among authors: winkler j. Stem Cell Reports. 2015 Sep 8;5(3):305-13. doi: 10.1016/j.stemcr.2015.07.010. Epub 2015 Aug 28. Stem Cell Reports. 2015. PMID: 26321143 Free PMC article.
GSK3ß-dependent dysregulation of neurodevelopment in SPG11-patient induced pluripotent stem cell model.
Mishra HK, Prots I, Havlicek S, Kohl Z, Perez-Branguli F, Boerstler T, Anneser L, Minakaki G, Wend H, Hampl M, Leone M, Brückner M, Klucken J, Reis A, Boyer L, Schuierer G, Behrens J, Lampert A, Engel FB, Gage FH, Winkler J, Winner B. Mishra HK, et al. Among authors: winkler j. Ann Neurol. 2016 May;79(5):826-840. doi: 10.1002/ana.24633. Ann Neurol. 2016. PMID: 26971897 Free PMC article.
α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy.
Ettle B, Kerman BE, Valera E, Gillmann C, Schlachetzki JC, Reiprich S, Büttner C, Ekici AB, Reis A, Wegner M, Bäuerle T, Riemenschneider MJ, Masliah E, Gage FH, Winkler J. Ettle B, et al. Among authors: winkler j. Acta Neuropathol. 2016 Jul;132(1):59-75. doi: 10.1007/s00401-016-1572-y. Epub 2016 Apr 8. Acta Neuropathol. 2016. PMID: 27059609 Free PMC article.
1,545 results