Wink S - Search Results

1

Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes.

Ter Braak B, Niemeijer M, Boon R, Parmentier C, Baze A, Richert L, Huppelschoten S, Wink S, Verfaillie C, van de Water B. Ter Braak B, et al. Among authors: wink s. Toxicol In Vitro. 2021 Jun;73:105107. doi: 10.1016/j.tiv.2021.105107. Epub 2021 Feb 3. Toxicol In Vitro. 2021. PMID: 33545341 Free article.

2

Quantitative high content imaging of cellular adaptive stress response pathways in toxicity for chemical safety assessment.

Wink S, Hiemstra S, Huppelschoten S, Danen E, Niemeijer M, Hendriks G, Vrieling H, Herpers B, van de Water B. Wink S, et al. Chem Res Toxicol. 2014 Mar 17;27(3):338-55. doi: 10.1021/tx4004038. Epub 2014 Feb 5. Chem Res Toxicol. 2014. PMID: 24450961 Review.

3

Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity.

Fredriksson L, Wink S, Herpers B, Benedetti G, Hadi M, de Bont H, Groothuis G, Luijten M, Danen E, de Graauw M, Meerman J, van de Water B. Fredriksson L, et al. Among authors: wink s. Toxicol Sci. 2014 Jul;140(1):144-59. doi: 10.1093/toxsci/kfu072. Epub 2014 Apr 20. Toxicol Sci. 2014. PMID: 24752500

4

Toxicogenomics directory of chemically exposed human hepatocytes.

Grinberg M, Stöber RM, Edlund K, Rempel E, Godoy P, Reif R, Widera A, Madjar K, Schmidt-Heck W, Marchan R, Sachinidis A, Spitkovsky D, Hescheler J, Carmo H, Arbo MD, van de Water B, Wink S, Vinken M, Rogiers V, Escher S, Hardy B, Mitic D, Myatt G, Waldmann T, Mardinoglu A, Damm G, Seehofer D, Nüssler A, Weiss TS, Oberemm A, Lampen A, Schaap MM, Luijten M, van Steeg H, Thasler WE, Kleinjans JC, Stierum RH, Leist M, Rahnenführer J, Hengstler JG. Grinberg M, et al. Among authors: wink s. Arch Toxicol. 2014 Dec;88(12):2261-87. doi: 10.1007/s00204-014-1400-x. Epub 2014 Nov 16. Arch Toxicol. 2014. PMID: 25399406

5

Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity.

Herpers B, Wink S, Fredriksson L, Di Z, Hendriks G, Vrieling H, de Bont H, van de Water B. Herpers B, et al. Among authors: wink s. Arch Toxicol. 2016 May;90(5):1163-79. doi: 10.1007/s00204-015-1536-3. Epub 2015 May 31. Arch Toxicol. 2016. PMID: 26026609 Free PMC article.

6

Alternative signaling network activation through different insulin receptor family members caused by pro-mitogenic antidiabetic insulin analogues in human mammary epithelial cells.

ter Braak B, Wink S, Koedoot E, Pont C, Siezen C, van der Laan JW, van de Water B. ter Braak B, et al. Among authors: wink s. Breast Cancer Res. 2015 Jul 19;17(1):97. doi: 10.1186/s13058-015-0600-5. Breast Cancer Res. 2015. PMID: 26187749 Free PMC article.

7

High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities.

Wink S, Hiemstra S, Herpers B, van de Water B. Wink S, et al. Arch Toxicol. 2017 Mar;91(3):1367-1383. doi: 10.1007/s00204-016-1781-0. Epub 2016 Jun 29. Arch Toxicol. 2017. PMID: 27358234 Free PMC article.

8

Comprehensive Landscape of Nrf2 and p53 Pathway Activation Dynamics by Oxidative Stress and DNA Damage.

Hiemstra S, Niemeijer M, Koedoot E, Wink S, Klip JE, Vlasveld M, de Zeeuw E, van Os B, White A, Water BV. Hiemstra S, et al. Among authors: wink s. Chem Res Toxicol. 2017 Apr 17;30(4):923-933. doi: 10.1021/acs.chemrestox.6b00322. Epub 2016 Dec 16. Chem Res Toxicol. 2017. PMID: 27982581

9

Dynamic imaging of adaptive stress response pathway activation for prediction of drug induced liver injury.

Wink S, Hiemstra SW, Huppelschoten S, Klip JE, van de Water B. Wink S, et al. Arch Toxicol. 2018 May;92(5):1797-1814. doi: 10.1007/s00204-018-2178-z. Epub 2018 Mar 3. Arch Toxicol. 2018. PMID: 29502165 Free PMC article.

10

Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases.

Zgheib E, Limonciel A, Jiang X, Wilmes A, Wink S, van de Water B, Kopp-Schneider A, Bois FY, Jennings P. Zgheib E, et al. Among authors: wink s. Front Genet. 2018 Oct 2;9:429. doi: 10.3389/fgene.2018.00429. eCollection 2018. Front Genet. 2018. PMID: 30333853 Free PMC article.

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