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HLA-E-restricted SARS-CoV-2-specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation.
Yang H, Sun H, Brackenridge S, Zhuang X, Wing PAC, Quastel M, Walters L, Garner L, Wang B, Yao X, Felce SL, Peng Y, Moore S, Peeters BWA, Rei M, Canto Gomes J, Tomas A, Davidson A, Semple MG, Turtle LCW, Openshaw PJM, Baillie JK, Mentzer AJ, Klenerman P; ISARIC4C Investigators; Borrow P, Dong T, McKeating JA, Gillespie GM, McMichael AJ. Yang H, et al. Among authors: wing pac. Sci Immunol. 2023 Jun 30;8(84):eabl8881. doi: 10.1126/sciimmunol.abl8881. Epub 2023 Jun 30. Sci Immunol. 2023. PMID: 37390223
iCollections methodology: workflow, results and lessons learned.
Blagoderov V, Penn M, Sadka M, Hine A, Brooks S, Siebert DJ, Sleep C, Cafferty S, Cane E, Martin G, Toloni F, Wing P, Chainey J, Duffell L, Huxley R, Ledger S, McLaughlin C, Mazzetta G, Perera J, Crowther R, Douglas L, Durant J, Scialabba E, Honey M, Huertas B, Howard T, Carter V, Albuquerque S, Paterson G, Kitching IJ. Blagoderov V, et al. Biodivers Data J. 2017 Sep 28;(5):e21277. doi: 10.3897/BDJ.5.e21277. eCollection 2017. Biodivers Data J. 2017. PMID: 29104442 Free PMC article.
The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication.
Zhuang X, Magri A, Hill M, Lai AG, Kumar A, Rambhatla SB, Donald CL, Lopez-Clavijo AF, Rudge S, Pinnick K, Chang WH, Wing PAC, Brown R, Qin X, Simmonds P, Baumert TF, Ray D, Loudon A, Balfe P, Wakelam M, Butterworth S, Kohl A, Jopling CL, Zitzmann N, McKeating JA. Zhuang X, et al. Among authors: wing pac. Nat Commun. 2019 Jan 22;10(1):377. doi: 10.1038/s41467-019-08299-7. Nat Commun. 2019. PMID: 30670689 Free PMC article.
A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis.
Wing PA, Davenne T, Wettengel J, Lai AG, Zhuang X, Chakraborty A, D'Arienzo V, Kramer C, Ko C, Harris JM, Schreiner S, Higgs M, Roessler S, Parish JL, Protzer U, Balfe P, Rehwinkel J, McKeating JA. Wing PA, et al. Life Sci Alliance. 2019 Mar 27;2(2):e201900355. doi: 10.26508/lsa.201900355. Print 2019 Apr. Life Sci Alliance. 2019. PMID: 30918010 Free PMC article.
A PCR assay to quantify patterns of HBV transcription.
D'Arienzo V, Magri A, Harris JM, Wing PAC, Ko C, Rubio CO, Revill PA, Protzer U, Balfe P, McKeating JA. D'Arienzo V, et al. Among authors: wing pac. J Gen Virol. 2021 Mar;102(3):001373. doi: 10.1099/jgv.0.001373. Epub 2019 Dec 17. J Gen Virol. 2021. PMID: 31846416 Free PMC article.
Hypoxic gene expression in chronic hepatitis B virus infected patients is not observed in state-of-the-art in vitro and mouse infection models.
Liu PJ, Harris JM, Marchi E, D'Arienzo V, Michler T, Wing PAC, Magri A, Ortega-Prieto AM, van de Klundert M, Wettengel J, Durantel D, Dorner M, Klenerman P, Protzer U, Giotis ES, McKeating JA. Liu PJ, et al. Among authors: wing pac. Sci Rep. 2020 Aug 24;10(1):14101. doi: 10.1038/s41598-020-70865-7. Sci Rep. 2020. PMID: 32839523 Free PMC article.
Cholesterol-modifying drugs in COVID-19.
Schmidt NM, Wing PAC, McKeating JA, Maini MK. Schmidt NM, et al. Among authors: wing pac. Oxf Open Immunol. 2020;1(1):iqaa001. doi: 10.1093/oxfimm/iqaa001. Epub 2020 Jun 18. Oxf Open Immunol. 2020. PMID: 33047740 Free PMC article.
Author Correction: Hypoxic gene expression in chronic hepatitis B virus infected patients is not observed in state-of-the-art in vitro and mouse infection models.
Liu PJ, Harris JM, Marchi E, D'Arienzo V, Michler T, Wing PAC, Magri A, Ortega-Prieto AM, van de Klundert M, Wettengel J, Durantel D, Dorner M, Klenerman P, Protzer U, Giotis ES, McKeating JA. Liu PJ, et al. Among authors: wing pac. Sci Rep. 2020 Nov 3;10(1):19332. doi: 10.1038/s41598-020-75963-0. Sci Rep. 2020. PMID: 33144658 Free PMC article.
Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter.
Wing PAC, Liu PJ, Harris JM, Magri A, Michler T, Zhuang X, Borrmann H, Minisini R, Frampton NR, Wettengel JM, Mailly L, D'Arienzo V, Riedl T, Nobre L, Weekes MP, Pirisi M, Heikenwalder M, Baumert TF, Hammond EM, Mole DR, Protzer U, Balfe P, McKeating JA. Wing PAC, et al. J Hepatol. 2021 Jul;75(1):64-73. doi: 10.1016/j.jhep.2020.12.034. Epub 2021 Jan 29. J Hepatol. 2021. PMID: 33516779 Free PMC article.
34 results